140 Biomarkers
| ID | Biomarker | Location | Application | Reference |
|---|---|---|---|---|
| 129 | P53 mutation | Colon, Rectum | Prognosis | Okubo R et al. Oncol Rep. 2001 |
| 167 | Tumor-associated DNA | Colon, Rectum | Prognosis | Lecomte T et al. Int J Cancer. 2002 |
| 201 | Fecal DNA | Colon, Rectum | Diagnosis | Boynton KA et al. Clin Chem. 2003 |
| 391 | Circulating cell-free DNA | Colon, Rectum | Diagnosis | Schwarzenbach H et al. Ann N Y Acad Sci. 2008 |
| 400 | Circulating DNA | Colon, Rectum | Treatment | Zitt M et al. Dis Markers. 2008 |
| 407 | UbcH10 gene | No Data | Diagnosis, Prognosis | Chen S et al. J Cancer Res Clin Oncol. 2010 |
| 431 | NGX6 | No Data | Diagnosis, Prognosis, Treatment | Liu M et al. BMC Cancer. 2010 |
| 434 | ABCB1/MDR1 gene polymorphisms | No Data | Prognosis | Balcerczak E et al. Int J Colorectal Dis. 2010 |
| 460 | Long interspersed nucleotide element-1 (LINE-1) | No Data | Prognosis | Kawakami K et al. Cancer Sci. 2010 |
| 471 | TLR-3 polymorphism | No Data | Prognosis | Castro FA et al. Eur J Cancer. 2011 |
| 479 | Methylation of DSC3 | No Data | Prognosis | Cui T et al. Br J Cancer. 2011 |
| 508 | CLOCK gene polymorphisms | Colon, Rectum | Prognosis | Zhou F et al. Cancer. 2012 |
| 554 | rs1954727 in ANGPT1 | Colon, Rectum | Prognosis | Dai J et al. PLoS One. 2012 |
| 565 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | No Data | Prognosis | Valladares-Ayerbes M et al. Int J Mol Sci. 2012 |
| 589 | MDM2 SNP309 | Colon, Rectum | Prognosis | Chaar I et al. Appl Immunohistochem Mol Morphol. 2013 |
| 607 | VEGF -2578C>A | Colon, Rectum | Prognosis | Jang MJ et al. Int J Clin Oncol. 2013 |
| 610 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | No Data | Prognosis, Treatment | Wu XS et al. World J Surg Oncol. 2012 |
| 665 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | Colon, Rectum | Treatment | Hsu HC et al. Int J Colorectal Dis. 2013 |
| 741 | Free circulating DNA (FCDNA) | Colon, Rectum | Prognosis | Cassinotti E et al. Int J Surg. 2013 |
| 760 | Leukocyte RTL | Colon, Rectum | Prognosis | Chen Y et al. Ann Oncol. 2014 |
| 773 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | No Data | Prognosis | He S et al. Biomed Pharmacother. 2014 |
| 778 | hMLH1 | Colon, Rectum | Prognosis | Wang Y et al. Med Oncol. 2014 |
| 779 | Tescalcin (TESC) | Colon | Diagnosis | Kang YH et al. Oncotarget. 2014 |
| 788 | Astrocyte elevated gene-1 (AEG-1) | No Data | Prognosis | Gnosa S et al. Br J Cancer. 2014 |
| 821 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | No Data | Diagnosis, Treatment | Hsu HC et al. Cell Signal. 2014 |
| 849 | ALU115 | Colon, Rectum | Diagnosis | Hao TB et al. Br J Cancer. 2014 |
| 854 | Long interspersed nucleotide element-1 (LINE-1) | Colon, Rectum | Prognosis | Inamura K et al. J Natl Cancer Inst. 2014 |
| 858 | CpG island methylation phenotype (CIMP) | Colon | Prognosis | Li X et al. Biomed Res Int. 2014 |
| 867 | Rs6475526 | Colon, Rectum | Prognosis | Lu S et al. PLoS One. 2014 |
| 895 | mTOR | Colon, Rectum | Prognosis | Wu S et al. Int J Clin Exp Pathol. 2015 |
| 896 | LC3 | Colon, Rectum | Prognosis | Wu S et al. Int J Clin Exp Pathol. 2015 |
| 903 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | No Data | Treatment | Lin YU et al. Oncol Lett. 2015 |
| 913 | Retinoid-interferon-induced mortality-19 (GRIM-19) | Colon, Rectum | Prognosis | Hao M et al. Hum Pathol. 2015 |
| 914 | PLA2G4C SNP (rs1549637) | No Data | Prognosis | Olsen RS et al. Acta Oncol. 2016 |
| 916 | Wilms' tumor gene (WT1) | No Data | Prognosis | Miyata Y et al. Cancer Biomark. 2015 |
| 947 | Forkhead box C2 (Foxc2) | No Data | Prognosis | Yang C et al. Oncol Lett. 2016 |
| 953 | CYP24A1 | Colon, Rectum | Prognosis | Sun H et al. Hum Pathol. 2016 |
| 956 | RAS mutation | Colon | Prognosis | Osumi H et al. Int J Cancer. 2016 |
| 957 | RAS mutation | Colon | Prognosis | Osumi H et al. Int J Cancer. 2016 |
| 984 | Methylated ctDNA (MetctDNA) | No Data | Prognosis | Garrigou S et al. Clin Chem. 2016 |
| 994 | Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) | Colon, Rectum | Prognosis | Stanisavljević L et al. Acta Oncol. 2016 |
| 1002 | Seven-gene signature (NHLRC3, ZDHHC21, PRR14L, CCBL1, PTPRB, PNPO,, PPIP5K2) | Colon, Rectum | Prognosis | Chen H et al. Oncotarget. 2016 |
| 1016 | Rassf1a rs2236947 | No Data | Prognosis | Sebio A et al. Pharmacogenomics J. 2016 |
| 1056 | Cell-free DNA (cfDNA) | Colon, Rectum | Diagnosis | Nagai Y et al. Oncotarget. 2017 |
| 1147 | TNFRSF10C | Colon, Rectum | Prognosis | Zhou, C et al. PeerJ. 2018 |
| 1153 | IL-13 SNP rs1800925, IL-4 SNP rs2243250 | Colon, Rectum | No Data | Shamoun, L et al. Clin Chim Acta. 2018 |
| 1156 | IL-17A G197A | Colon, Rectum | Diagnosis | Al Obeed, O A et al. Cancer Manag Res. 2018 |
| 1158 | Circulating cell-free DNA (cfDNA) | No Data | Diagnosis, Prognosis | Niu, Z et al. Acta Biochim Biophys Sin (Shanghai). 2018 |
| 1178 | CDO1 methylation | Colon | Prognosis | Yokoi, K et al. Ann Surg Oncol. 2019 |
| 1181 | FCGR2A | Colon, Rectum | Prognosis | Shepshelovich, D et al. Cancer Med. 2018 |
| 1212 | G4C14-A4T14 polymorphism | No Data | No Data | Meng, J et al. Biosci Rep. 2018 |
| 1234 | liver kinase B1 gene (LKB1, also known as serine/threonine kinase 11, STK11) | Colon, Rectum | No Data | Chen, Y et al. Oncol Rep. 2019 |
| 1237 | p16 promoter methylation | Colon, Rectum | Diagnosis, Prognosis | Karam, R A et al. J Cell Biochem. 2018 |
| 1245 | TNF-α -238 G/A polymorphism | Colon, Rectum | No Data | Huang, X et al. Biosci Rep. 2019 |
| 1246 | formin 2 (FMN2) | Colon, Rectum | Diagnosis | Li, D J et al. World J Gastroenterol. 2018 |
| 1249 | APC2 | No Data | No Data | He, Y et al. Dis Markers. 2018 |
| 1269 | Six-gene Assay(CEA, EpCAM, CK19, MUC1, EGFR and C-Met) | No Data | No Data | Shou, X et al. Mol Oncol. 2019 |
| 1281 | circulating tumor DNA (ctDNA) | Colon | Diagnosis | Osumi, H et al. Cancer Med. 2019 |
| 1301 | significant difference in TRBV and TRBJ gene usage | No Data | Diagnosis, Treatment | Liu, X et al. Mol Genet Genomic Med. 2019 |
| 1322 | WNT10A methylation | Colon, Rectum | Diagnosis | Jiang, H et al. Am J Transl Res. 2018 |
| 1323 | large variation in DNMT1 expression | Colon | No Data | Honeywell, R J et al. Nucleosides Nucleotides Nucleic Acids. 2018 |
| 1327 | SOX9 and TGFBI gene | Colon, Rectum | Diagnosis | Zhang, H et al. J Cell Biochem. 2019 |
| 1349 | c-MYC | Colon, Rectum | Prognosis | Lee, K S et al. Sci Rep. 2019 |
| 1354 | Hypoxia-related gene (HRG) | Colon, Rectum | Prognosis | Lee, J H et al. Sci Rep. 2019 |
| 1366 | KRAS mutations | No Data | No Data | Xie, W et al. Cancer Med. 2019 |
| 1374 | ATM gene | No Data | Prognosis | Randon, G et al. Sci Rep. 2019 |
| 1375 | CHST7 methylation | Colon, Rectum | No Data | Bi, H et al. Dig Dis Sci. 2019 |
| 1389 | MPPED2 | Colon, Rectum | Diagnosis | Gu, S et al. Clin Epigenetics. 2019 |
| 1397 | GST Pi 1 (GSTP1) polymorphism | Colon, Rectum | No Data | Katayanagi, S et al. Oncol Lett. 2019 |
| 1411 | stool DNA-based SDC2 methylation(syndecan-2) | No Data | No Data | Han, Y D et al. Clin Epigenetics. 2019 |
| 1413 | circulating CCAT2 | Colon, Rectum | Prognosis | Wang, L et al. Biomed Pharmacother. 2019 |
| 1418 | 4-gene signature (ACVR2A, APC, DOCK2, and POLE) | Colon, Rectum | No Data | Ge, W et al. Cancer Manag Res. 2019 |
| 1428 | The promoter of OGDHL gene hypermethylated | Colon, Rectum | Diagnosis | Khalaj-Kondori, M et al. Curr Probl Cancer. 2019 |
| 1434 | rs5030740 | Colon, Rectum | Prognosis | Li, S et al. J Gastroenterol. 2019 |
| 1436 | RAS mutation | No Data | No Data | Morgan, Z et al. J Surg Res. 2019 |
| 1438 | KCNQ1OT1 | Colon | Prognosis | Zhang, K et al. Future Oncol. 2019 |
| 1657 | Cell-free circulating DNAs (cfcDNAs) | Colon, Rectum | Prognosis | Agah S et al. Cancer Invest. 2017 |
| 1719 | circulating tumour DNA(ctDNA) | Rectum | Prognosis | Tie J et al. Gut. 2019 |
| 1725 | DNA methylation at BMP3 and VAV3 | Colon, Rectum | Diagnosis | Kisiel JB et al. Clin Gastroenterol Hepatol. 2019 |
| 1770 | circulating tumour DNA(ctDNA) | Colon, Rectum | Prognosis | Yang YC et al. Biosci Rep. 2018 |
| 1829 | early ctDNA | Colon, Rectum | Prognosis, Treatment | Vandeputte C et al. Oncotarget. 2018 |
| 1895 | MPO SNP rs2333227 | Colon, Rectum | Prognosis | Meng Q et al. Cancer Res. 2018 |
| 1991 | BRAFV600E mutation | Colon, Rectum | Prognosis | Eachkoti R et al. Mutagenesis. 2018 |
| 2058 | SLC30A10, CLDN1, INHBA methylation | Colon, Rectum | Diagnosis | Kerachian, M. A et al. Sci Rep. 2020 |
| 2083 | Genomic variation | Rectum | Treatment | Douglas, J. K et al. Mol Cell Oncol. 2020 |
| 2086 | cfDNA | Colon, Rectum | Prognosis | Zhong, Y et al. Cell Mol Biol (Noisy-le-grand). 2020 |
| 2090 | SOX21 | Colon, Rectum | Diagnosis | Moradi, K et al. Indian J Cancer. 2020 |
| 2093 | KCNB1 | Colon, Rectum | Treatment | Barbirou, M et al. Tumour Biol. 2020 |
| 2096 | PALB2 | Colon, Rectum | Prognosis | Pan, W et al. Comput Biol Chem. 2020 |
| 2098 | (ct) DNA | Colon, Rectum | Prognosis | Beagan, J. J et al. J Clin Med. 2020 |
| 2100 | NLRP1 rs12150220 and SRL rs13334970 | Colon, Rectum | No Data | Barat, A et al. Sci Rep. 2020 |
| 2102 | SEPT9 | Colon, Rectum | Treatment | Leon Arellano, M et al. Dis Markers. 2020 |
| 2111 | Methylation of SEPT9 and SDC2 | Colon, Rectum | Diagnosis | Zhao, G et al. Front Genet. 2020 |
| 2133 | ctDNA | Colon, Rectum | Prognosis | Boysen, A. K et al. Acta Oncol. 2020 |
| 2154 | ctDNA | Colon, Rectum | Prognosis, Treatment | Unseld, M et al. Int J Cancer. 2021 |
| 2155 | ctDNA | Colon, Rectum | Prognosis, Treatment | Zou, D et al. Carcinogenesis. 2020 |
| 2157 | SCTR | Colon, Rectum | Diagnosis | Li, D et al. Cancer Sci. 2020 |
| 2161 | SMAD3 | Colon, Rectum | Diagnosis | Ansar, M et al. Int J Mol Sci. 2020 |
| 2164 | INHBB | Colon, Rectum | Prognosis | Yuan, J et al. Biomed Res Int. 2020 |
| 2165 | Genomic amplification of chromosome 20q13.33 | Colon, Rectum | Diagnosis, Prognosis | Bui, V. M et al. BMC Med Genomics. 2020 |
| 2172 | ctDNA | Colon, Rectum | Prognosis | Petrillo, A et al. Curr Drug Targets. 2021 |
| 2174 | CEP55 | Colon, Rectum | Diagnosis, Prognosis | Lin, K et al. Immun Inflamm Dis. 2021 |
| 2179 | CLCA1 | Colon, Rectum | Diagnosis, Prognosis | Wei, F. Z et al. Front Oncol. 2020 |
| 2187 | cfDNA | Colon, Rectum | Prognosis | Ørntoft, M. W et al. Int J Cancer. 2021 |
| 2193 | SOX21 promoter methylation | Colon, Rectum | Diagnosis | Moradi, K et al. Indian J Cancer. 2021 |
| 2195 | RAS | Colon, Rectum | Prognosis | Schrock, A. B et al. Oncologist. 2021 |
| 2196 | ctDNA | Colon, Rectum | Prognosis | Boniface, C et al. Diagnostics (Basel). 2021 |
| 2201 | Small EVs-Associated DNA | Colon, Rectum | Prognosis | Galbiati, S et al. Pharmaceuticals (Basel). 2021 |
| 2206 | SHISA3 | Colon, Rectum | Diagnosis | Tang, S. H et al. Chin J Physiol. 2021 |
| 2213 | ctDNA | Rectum | Prognosis | Vidal, J et al. Clin Cancer Res. 2021 |
| 2221 | circulating MT-ND1 | Colon, Rectum | Diagnosis, Prognosis | Xu, Y et al. Bosn J Basic Med Sci. 2021 |
| 2224 | SELE | Colon, Rectum | Prognosis | Li, N et al. J Int Med Res. 2021 |
| 2233 | EHD3 | Colon, Rectum | Prognosis | Wang, Y. H et al. Biomedicines. 2021 |
| 2235 | IL2RB | Colon, Rectum | Treatment | Alderdice, M et al. NAR Genom Bioinform. 2021 |
| 2236 | cfDNA | Colon, Rectum | Treatment | Pastor, B et al. Mol Oncol. 2021 |
| 2240 | SDC2 and TFPI2 | Colon, Rectum | Diagnosis | Zhang, W et al. Cancer Manag Res. 2021 |
| 2241 | FAM83A and IDO1 | Colon, Rectum | Prognosis | Liu, Z et al. Front Oncol. 2021 |
| 2251 | PDE9A | Colon, Rectum | Prognosis | Susmi, T. F et al. BMC Cancer. 2021 |
| 2258 | ctDNA | Colon, Rectum | Prognosis, Treatment | To, Y. H et al. Pharmacoeconomics. 2021 |
| 2265 | cfDNA | Colon, Rectum | Prognosis | Zhu, F et al. J Oncol. 2021 |
| 2275 | METTL14 | Rectum | Prognosis | Cai, C et al. Front Oncol. 2021 |
| 2293 | LAMTOR5 | Colon, Rectum | Prognosis | Zaniani, N. R et al. Mol Biol Rep. 2021 |
| 2301 | NRIP1 | Colon, Rectum | Prognosis | Palassin, P et al. Cancers (Basel). 2021 |
| 2303 | c-Met/EGFR | Colon, Rectum | Prognosis, Treatment | Lawal, B et al. Front Pharmacol. 2021 |
| 2304 | SYK Gene | Colon, Rectum | Prognosis | Biswas, P et al. J Pers Med. 2021 |
| 2315 | DNA ploidy | Colon, Rectum | Prognosis | Peng, J et al. Cancer Cell Int. 2021 |
| 2318 | Complement component 3 (C3) | Colon, Rectum | Prognosis, Treatment | He, X. S et al. Front Mol Biosci. 2021 |
| 2319 | ctDNA | Colon, Rectum | Prognosis | Benhaim, L et al. Eur J Cancer. 2021 |
| 2327 | KIAA1522 | Colon, Rectum | Prognosis | Yi, X et al. Cell Signal. 2022 |
| 2349 | Circulating Cell Free DNA (cfDNA) | Colon, Rectum | Prognosis, Treatment | Eskander, N. S et al. Asian Pac J Cancer Prev. 2022 |
| 2360 | ctDNA | Colon, Rectum | Prognosis | Hallermayr, A et al. Cancers (Basel). 2022 |
| 2368 | mSEPT9 | Colon, Rectum | Prognosis | Huang, M et al. BMC Gastroenterol. 2022 |
| 2369 | SLC6A1 | Colon, Rectum | Prognosis | Wang, Q. Q et al. Dis Markers. 2022 |
| 2371 | FREM2 Mutation | Colon, Rectum | Prognosis | Du, H et al. Front Mol Biosci. 2022 |
| 2386 | Septin 9 Gene Hypermethylation | Colon, Rectum | Recurrences | Leon Arellano, M et al. Diagnostics (Basel). 2022 |
| 2395 | AHCYL1 | Colon, Rectum | Prognosis, Treatment | Li, X et al. J Oncol. 2022 |
| 2401 | cg01419567 (ZFHX4), cg26238800 (ZNF334), cg13562911 (ELOVL2), cg16475705 (UNC5C), cg06921368 (LOC146880), cg20506550 (SFMBT2) and cg12087643 (GFRA1) | Colon, Rectum | Prognosis | Wang, W et al. Front Oncol. 2022 |
| 2422 | Circulating tumour DNA (ctDNA) | Colon, Rectum | Prognosis | Jones, R. P et al. Eur J Cancer. 2021 |
| 2429 | WIF1 methylation | Colon, Rectum | Diagnosis | Hu, H et al. Oncotarget. 2018 |
| 2432 | SFRP1, SFRP2, NDRG4 and VIM DNA hypermethylation | Colon, Rectum | Diagnosis | Mojtabanezhad Shariatpanahi, A et al. PLoS One. 2018 |