Chapter VI Diseases of the nervous system

204 biomarkers

Chapter Eye_Biomarker Systematic_Disease Category
Chapter VI a decrease in retinal vascularization density in the superficial plexus of the parafoveal retina multiple sclerosis(MS) Bio-imaging
Chapter VI a high yield of AbetaPP and Abeta in the ocular fluids alzheimer’s disease(AD) Protein
Chapter VI abnormally high Eye Blink Rate (EBR) mild cognitive impairment (MCI) Eye measures
Chapter VI affecting the cornea multiple sclerosis(MS) Disease
Chapter VI aggregated α-synuclein near or at the inner retinal surface parkinson's disease (PD) Protein
Chapter VI amyloid-β (Aβ) levels in the retinal tissue/ the ocular biomarkers in anterior and posterior segments of the eye including the cornea, aqueous humour (AH), crystalline lens, and retina alzheimer’s disease(AD) Bio-imaging
Chapter VI amyloid-β (Aβ) signatures in the retinal tissue、 Aβ accumulates in the lens alzheimer’s disease(AD) Protein
Chapter VI angio-OCT multiple sclerosis(MS) Bio-imaging
Chapter VI anti-AQP4 antibody neuromyelitis optica (NMO) Protein
Chapter VI aqueous humor Aβ alzheimer’s disease(AD) Protein
Chapter VI arteriole-to-venule ratio of retinal vessel obstructive sleep apnea syndrome Bio-imaging
Chapter VI atrophy of the pRNFL and mGCIPL multiple sclerosis(MS) Bio-imaging
Chapter VI Aβ deposition in the eye alzheimer’s disease(AD) Protein
Chapter VI Aβ plaques in the retina alzheimer’s disease(AD) Bio-imaging
Chapter VI bruch membrane opening and maximal RNFL thickness increased intracranial pressure in idiopathic intracranial hypertension Bio-imaging
Chapter VI bruch's membrane opening-minimum rim widt multiple sclerosis(MS) Bio-imaging
Chapter VI cataract myotonic dystrophy type 1 (DM1) Disease
Chapter VI change of INL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI choroidal thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI choroidal thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI choroidal thickness and vascular morphology alzheimer’s disease(AD) Bio-imaging
Chapter VI choroidal thinning alzheimer’s disease(AD) Bio-imaging
Chapter VI choroidal-retinal thickness alterations parkinson's disease (PD) Bio-imaging
Chapter VI color vision parkinson's disease (PD) Eye measures
Chapter VI corneal IVCM and corneal sensitivity testing diabetic peripheral and cardiac autonomic neuropathy Eye measures
Chapter VI corneal nerve fiber density (CNFD), corneal nerve branch density, corneal nerve fiber length, corneal total branch density, and corneal nerve fiber area parkinson's disease (PD) Eye measures
Chapter VI corneal nerve fiber density (CNFD),corneal nerve fiber length (CNFL) was decreased;corneal nerve branch density (CNBD) was significantly increased parkinson's disease (PD) Eye measures
Chapter VI corneal nerve fiber loss multiple sclerosis(MS) Eye measures
Chapter VI corneal nerve fibre density , corneal nerve branch density , corneal total branch density , and corneal nerve fibre length were significantly lower parkinson's disease (PD) Eye measures
Chapter VI corneal nerve loss and increased dendritic cells meseared by Corneal confocal microscopy (CCM) multiple sclerosis(MS) Eye measures
Chapter VI corneal neural network and conjunctival vasculature alzheimer’s disease(AD) Eye measures
Chapter VI decrease in macular volume and temporal RNFL huntington's disease(HD) Bio-imaging
Chapter VI decreased peripapillary nerve fiber layer thickness and increased optic nerve head parameters(average cup/disk ratio and the vertical cup/disk ratio ) obstructive sleep apnea syndrome (OSAS) Bio-imaging
Chapter VI decreased Peripapillary RNFL, global, and in superior quadrant alzheimer’s disease(AD), mild cognitive impairment (MCI) Bio-imaging
Chapter VI decreased Retinal nerve fiber layer (RNFL) multiple sclerosis(MS) Bio-imaging
Chapter VI decreased retinal VD and PFD as well as choroidal structural changes parkinson's disease (PD) Bio-imaging
Chapter VI decreased RNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI diminished retinal nerve fiber layer thickness multiple sclerosis(MS) Bio-imaging
Chapter VI dyschromatopsia multiple sclerosis(MS) Eye measures
Chapter VI eyes-closed (EC) to eyes-open (EO) alpha reactivity alzheimer’s disease(AD) Eye measures
Chapter VI fluorescence lifetime imaging ophthalmoscopy alzheimer’s disease(AD) Bio-imaging
Chapter VI foveal and peripapillary vascular decrements migraine with aura Bio-imaging
Chapter VI foveal and peripapillary vascular decrements migraine with aura Bio-imaging
Chapter VI foveal avascular zone neuromyelitis optica spectrum disorders Bio-imaging
Chapter VI ganglion cell + inner plexiform layer (GCIP) atrophy multiple sclerosis(MS) Bio-imaging
Chapter VI ganglion cell and retinal layer atrophy alzheimer’s disease(AD) Bio-imaging
Chapter VI ganglion cell complex thinning parkinson's disease (PD) Bio-imaging
Chapter VI ganglion cell layer (GCL) alterations multiple sclerosis and optic neuritis Bio-imaging
Chapter VI ganglion cell layer thickening obstructive sleep apnea (OSA) Bio-imaging
Chapter VI ganglion cell layer thinning alzheimer’s disease(AD) Bio-imaging
Chapter VI GCIPL and pRNFL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI GCIPL, and to a lesser degree pRNFL relapsing multiple sclerosis Bio-imaging
Chapter VI GCL + IPL thickness early multiple sclerosis Bio-imaging
Chapter VI GCL + IPL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI glycine receptors(ganglion cell responses) spastic Protein
Chapter VI impaired retinal tissue perfusion multiple sclerosis(MS) Bio-imaging
Chapter VI increased INL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI inferonasal GCLIPL, mean GCLIPL, and pRNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI inner nuclear layer (INL) volume changes multiple sclerosis(MS) Bio-imaging
Chapter VI inner retinal layer thinning :Temporal pRNFL, macular RNFL (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer and outer plexiform layer thicknesses and IPL, retinal pigment epithelium and outer macular volume were found lower huntington's disease(HD) Bio-imaging
Chapter VI inner retinal layers (RNFL and GCIPL) multiple sclerosis(MS) Bio-imaging
Chapter VI inner retinal layers thinning mild cognitive impairment (MCI) Bio-imaging
Chapter VI inter-eye differences of ≥4 μm for GCIPL and to a lesser degree ≥5 μm for RNFL optic neuritis in multiple sclerosis Bio-imaging
Chapter VI lower corneal nerve fiber density (NFD);The total nerve fiber length and the number of nerve branches were significantly decreased;nerve tortuosity was increased chronic inflammatory demyelinating polyneuropathy (CIDP) Eye measures
Chapter VI lower Corneal nerve fibre density (CNFD), branch density (CNBD) and fibre length (CNFL) ; higher fibre tortuosity (CNFT) multiple sclerosis(MS) Eye measures
Chapter VI lower ganglion cell + inner plexiform layer (GCIPL) thicknesses,inner nuclear layer thicknesses stiff-person syndrome Bio-imaging
Chapter VI lower retinal capillary skeleton and perfusion densities and capillary complexity in the total annular zone and all quadrant sectors parkinson's disease (PD) Bio-imaging
Chapter VI lower thickness of pRNFL , total macular, and subfoveal choroid mild cognitive impairment (MCI) Bio-imaging
Chapter VI lysozyme alzheimer’s disease(AD) Other
Chapter VI macular GCIPL thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI macular GCIPL thickness mild cognitive impairment (MCI) Bio-imaging
Chapter VI macular thickness parkinson's disease (PD) Bio-imaging
Chapter VI macular thickness and the retinal nerve fibre layer alzheimer’s disease(AD), mild cognitive impairment (MCI) Bio-imaging
Chapter VI macular thinning, RNFL, thinning of both inner and outer nuclear cell layers,ganglion cell layer multiple sclerosis(MS) Bio-imaging
Chapter VI mfVEP amplitude multiple sclerosis(MS) Eye measures
Chapter VI mGCIPL thickness,peripapillary RNFL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI microcystic macular oedema multiple sclerosis(MS) Bio-imaging
Chapter VI molecular repository of tears multiple sclerosis(MS) Metabolite
Chapter VI MRI diffusion restriction in the optic nerve head idiopathic intracranial hypertension(IIH) Bio-imaging
Chapter VI NFL thickness, blood flow, ONH damage, alzheimer’s disease(AD) Bio-imaging
Chapter VI NH volume (ONHV) and height (ONHH) in 3D volume scans idiopathic intracranial hypertension(IIH) Bio-imaging
Chapter VI OCT newly diagnosed IIH patients Bio-imaging
Chapter VI OCT (RNFL thickness) multiple sclerosis(MS) Bio-imaging
Chapter VI OCTA early optic nerve damage in idiopathic intracranial hypertension Bio-imaging
Chapter VI oculomotor testing parkinson's disease (PD) Eye measures
Chapter VI oligomeric α-Syn (α-SynOligo), total α-Syn (α-SynTotal) in reflex tears parkinson's disease (PD) Protein
Chapter VI optic disk color:papillary paleness alzheimer’s disease(AD) Eye measures
Chapter VI optic nerve head morphology, retinal amyloid deposition, microvascular morphology and densities, blood flow, and electrophysiological markers alzheimer’s disease(AD), mild cognitive impairment (MCI), and preclinical AD. Bio-imaging
Chapter VI oxygen levels in the retina alzheimer’s disease(AD) Eye measures
Chapter VI oxygen levels in the retina multiple sclerosis(MS) Eye measures
Chapter VI palpebral portion of the orbicularis oculi muscle myasthenia gravis (MG) Eye measures
Chapter VI pattern visual evoked potentials (PVEP):P(100) latency was significantly delayed,P(100) amplitude was significantly reduced multiple sclerosis(MS) Eye measures
Chapter VI periodic acid Schiff-positive round profiles were identified in the retinal nerve fiber layer ; P-NF-positive spheroid density was significantly increased in the retinal nerve fiber layer amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI peripapillary Bruch's membrane (pp-BM) shape chronic intracranial pressure Bio-imaging
Chapter VI peripapillary region vessel density reduction multiple sclerosis(MS) Bio-imaging
Chapter VI peripapillary retinal nerve fiber layer (pRNFL) thickness, macular volume (MV) multiple sclerosis(MS) Bio-imaging
Chapter VI peripapillary retinal nerve fibre layer (NFL) thickness, macular ganglion cell complex (GCC) thickness and Optic Nerve Head Flow Index (ONH-FI) multiple sclerosis(MS) Bio-imaging
Chapter VI peripapillary retinal nerve fibre layer thinning rate relapsing-remitting multiple sclerosis Bio-imaging
Chapter VI peripapillary RNFL friedreich's ataxia Bio-imaging
Chapter VI peripapillary vessel density neuromyelitis optica spectrum disorders Bio-imaging
Chapter VI photopic negative response (PhNR) idiopathic intracranial hypertension(IIH) Eye measures
Chapter VI presence of ONH pallor cerebral palsy of perinatal origin Eye measures
Chapter VI pRNFL relapsing-remitting MS Bio-imaging
Chapter VI pRNFL reduction alzheimer’s disease(AD) Bio-imaging
Chapter VI pRNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI pRNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI pRNFL; macular volume; macular GCL-IPL complexes mild cognitive impairment (MCI) Bio-imaging
Chapter VI pupil flash response alzheimer’s disease(AD) Eye measures
Chapter VI pupillary unrest parkinson's disease (PD) Eye measures
Chapter VI pupillometry parkinson's disease (PD) Eye measures
Chapter VI PVEP(P100 latencies were significantly delayed and P100 amplitudes were significantly reduced) multiple sclerosis(MS) Eye measures
Chapter VI reduced corneal nerve fiber densities and lengths small fiber neuropathy in early Parkinson's disease Eye measures
Chapter VI reduced corneal nerve fiber density Chronic migraine Bio-imaging
Chapter VI reduction in corneal nerve fiber density (CNFD, fibers/mm2) , branch density (CNBD, branches/mm2) , and fiber length meseared by Corneal confocal microscopy (CCM) mild cognitive impairment (MCI) Eye measures
Chapter VI reduction of average-RNFL , temporal-RNFL, and papillo-macular bundle-RNFL multiple sclerosis(MS) Bio-imaging
Chapter VI reduction of the RNFL thickness assessed by SLP obstructive sleep apnea (OSA) Bio-imaging
Chapter VI reductions in the thickness of average, temporal, and inferior pRNFL and overall mGCIPL de novo Parkinson's disease Bio-imaging
Chapter VI repetitive nerve stimulation (RNS) testing of the palpebral portion of the orbicularis oculi muscle generalized myasthenia gravis Eye measures
Chapter VI retinal alteration arachnoid cyst of the pineal region Bio-imaging
Chapter VI retinal and choroidal vascular pathologies alzheimer's type dementia Bio-imaging
Chapter VI retinal and lens amyloid-beta accumulation alzheimer’s disease(AD) Protein
Chapter VI retinal blood flow ,electrical activity in the macula alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal capillary complexity parkinson's disease (PD) Bio-imaging
Chapter VI retinal changes amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI retinal changes parkinson's disease (PD) Eye measures
Chapter VI retinal hyperspectral imaging brain Aβ load of AD Bio-imaging
Chapter VI retinal layer thickness preclinical Alzheimer's disease Eye measures
Chapter VI retinal layers reduction multiple sclerosis(MS) Bio-imaging
Chapter VI retinal microvascular density parkinson's disease (PD) Bio-imaging
Chapter VI retinal microvascular density parkinson's disease (PD) Bio-imaging
Chapter VI retinal microvasculature alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal microvasculature change parkinson's disease (PD) Bio-imaging
Chapter VI retinal nerve fiber layer obstructive sleep apnea syndrome Bio-imaging
Chapter VI peripapillary retinal nerve fiber layer (pRNFL) thinning multiple sclerosis(MS) Bio-imaging
Chapter VI retinal nerve fiber layer (RNFL) thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal nerve fiber layer (RNFL) thickness alzheimer’s disease(AD), mild cognitive impairment (MCI) Bio-imaging
Chapter VI retinal nerve fiber layer (RNFL) thinning parkinson's disease (PD) Bio-imaging
Chapter VI retinal nerve fiber layer loss, and retinal vascular changes alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal nerve fiber layer thickening autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) Bio-imaging
Chapter VI retinal nerve fiber layer thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal nerve fiber layer thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI retinal nerve fiber layer thickness multiple sclerosis(MS) Bio-imaging
Chapter VI retinal nerve fiber layer thickness (RNFL), other retinal layers thicknesses such as outer nuclear layer (ONL) and inner nuclear layer (INL) and changes in the retinal blood vessels amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI retinal nerve fiber layer thickness and ganglion-cell layer-inner plexiform layer thickness;microcystic macular edema and associated thickening of the retinal inner nuclear layer multiple sclerosis(MS) Bio-imaging
Chapter VI retinal nerve fiber layer thinning multiple sclerosis(MS) Bio-imaging
Chapter VI retinal SVP density multiple sclerosis(MS) Bio-imaging
Chapter VI retinal tau alzheimer’s disease(AD) Protein
Chapter VI retinal thickness and microvascular pathway REM sleep behavior disorder Bio-imaging
Chapter VI retinal vascular density multiple sclerosis(MS) Bio-imaging
Chapter VI retinal vascularization density multiple sclerosis(MS) Bio-imaging
Chapter VI retinal vessel structures multiple sclerosis(MS) Bio-imaging
Chapter VI rHSI-based ΔOD values alzheimer’s disease(AD) Other
Chapter VI RNFL atrophy and the presence of oligoclonal bands (OCBs) multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thickness demyelinating diseases Bio-imaging
Chapter VI RNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thickness multiple sclerosis disease Bio-imaging
Chapter VI RNFL thinning amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI RNFL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI RNFL thinning multiple sclerosis(MS) Bio-imaging
Chapter VI RNFLT thinning multiple sclerosis(MS) Bio-imaging
Chapter VI RNS testing of the palpebral portion of the orbicularis oculi muscle myasthenia gravis (MG) Eye measures
Chapter VI spontaneous eye-blink obstructive sleep apnoea (OSA) Symptom
Chapter VI static and dynamic pupillary responses obstructive sleep apnea syndrome (OSAS) Eye measures
Chapter VI superficial retinal microvascular plexuses multiple sclerosis(MS) Bio-imaging
Chapter VI tear protein level alterations parkinson's disease (PD) Protein
Chapter VI temporal and superior RNFL sectors thinning huntington's disease(HD) Bio-imaging
Chapter VI testing visual fields multiple sclerosis(MS) Eye measures
Chapter VI the average retinal nerve fiber layer (RNFL) thickness , total macular thickness, and macular volume were decreased parkinson's disease (PD) Bio-imaging
Chapter VI the center 1 mm and temporal outer ETDRS regions of retinal thickness parkinson's disease (PD) Bio-imaging
Chapter VI the changes in the metabolism of monoamines in the eye and eyelid parkinson's disease (PD) Metabolite
Chapter VI the decrease in macular retinal and thickness huntington's disease(HD) Bio-imaging
Chapter VI the decreased RNFL thickness alzheimer’s disease(AD) Bio-imaging
Chapter VI the decreased RNFL thickness mild cognitive impairment (MCI) Bio-imaging
Chapter VI the injury pattern of INL neuromyelitis optica (NMO) Bio-imaging
Chapter VI the peripapillary RNFL layer thickness parkinson's disease (PD) Bio-imaging
Chapter VI the rapidly declining RNFL and GCIPL;ONH parameters of rim area, average cup-to-disc (C:D) ratio, and cup volume familial dysautonomia (FD) disease Bio-imaging
Chapter VI the ratio of optic nerve sheath diameter to eyeball transverse diameter (ONSD/ETD) intracranial hypertension in traumatic brain injury (TBI) patients Eye measures
Chapter VI the retinal choroid alzheimer's dementia Bio-imaging
Chapter VI the retinal nerve fiber layer (RNFL) multiple sclerosis(MS) Bio-imaging
Chapter VI the retinal nerve fibre layer (RNFL) multiple sclerosis(MS) Bio-imaging
Chapter VI the retrograde loss of nerve fiber layer tissue in the retina and optic nerve alzheimer’s disease(AD) Bio-imaging
Chapter VI the RNFL thickness multiple sclerosis(MS) Bio-imaging
Chapter VI the structure and microvasculature of the retina and choroid parkinson's disease (PD) Bio-imaging
Chapter VI the thickness of peripapillary retinal nerve fiber layer (pRNFL), total macular , and subfoveal choroid were significantly reduced alzheimer’s disease(AD) Bio-imaging
Chapter VI thickening of the OPL parkinson's disease (PD) Bio-imaging
Chapter VI thinned RNFL amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI thinner RNFL dementia, alzheimer’s disease Bio-imaging
Chapter VI thinning in both the inner and outer layers of the retina alzheimer’s disease(AD) Bio-imaging
Chapter VI thinning of RNFL parkinson's disease (PD) Bio-imaging
Chapter VI thinning of RNFL and GCC multiple sclerosis(MS) Bio-imaging
Chapter VI thinning of RNFL and GCC multiple sclerosis(MS) Bio-imaging
Chapter VI thinning of the inner nuclear layer (INL) and the retinal nerve fibre layer amyotrophic lateral sclerosis (ALS) Bio-imaging
Chapter VI thinning of the peripapillary retinal nerve fiber layer and the combined ganglion cell and inner plexiform layers parkinson's disease (PD) Bio-imaging
Chapter VI thinning of the retinal nerve fibre layer (RNFL) and the fovea parkinson's disease (PD) Bio-imaging
Chapter VI thinning of the RNFL and superior hemiretina alzheimer’s disease(AD) Bio-imaging
Chapter VI uveitis multiple sclerosis(MS) Disease
Chapter VI UWF retinal imaging alzheimer’s disease(AD) Bio-imaging
Chapter VI vessel density reduction in retina multiple sclerosis(MS) Bio-imaging
Chapter VI visual function parkinson's disease (PD) Eye measures
Chapter VI visuospatial perception (VSP) functions alzheimer’s disease(AD) Eye measures
Chapter VI α-SynTotal was decreased , α-SynOligo and the ratio of α-SynOligo/α-SynTotal were increased parkinson's disease (PD) Protein