561 biomarker pathways
| Pathway ID | Term Description | Observed Gene Count | Background Gene Count | Strength | Biomarkers |
|---|---|---|---|---|---|
| GO:0005615 | extracellular space | 36 | 3195 | 0.6 | CEACAM6,VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,VWF,ITGA2B,MCAM,SOD1,APP,AZGP1,PTX3,CD5L,FLNA,MMP9,SRC,PCNA,EDN1,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,CFB,HTN3,CFL1,CRYAB,PGF,RBP3,VEGFA |
| GO:0005576 | extracellular region | 38 | 4166 | 0.51 | CEACAM6,VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,VWF,ITGA2B,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,FGF13,CD5L,FLNA,MMP9,SRC,PCNA,EDN1,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,CFB,HTN3,CFL1,CRYAB,PGF,RBP3,VEGFA |
| GO:1903561 | extracellular vesicle | 20 | 2121 | 0.53 | VCL,C5,APOB,CTSD,SERPINF1,VWF,ITGA2B,SOD1,APP,AZGP1,FLNA,MMP9,SRC,PCNA,CFI,FIGNL1,CFB,CFL1,CRYAB,RBP3 |
| GO:0031982 | vesicle | 27 | 3879 | 0.39 | CEACAM6,VCL,HGF,C5,APOB,CTSD,SERPINF1,VWF,ITGA2B,SOD1,APP,AZGP1,PTX3,FLNA,MMP9,SRC,PCNA,EDN1,CFI,TNF,FIGNL1,CFB,CFL1,CRYAB,AKT1,RBP3,VEGFA |
| GO:0070062 | extracellular exosome | 19 | 2099 | 0.51 | VCL,C5,APOB,CTSD,SERPINF1,VWF,ITGA2B,SOD1,APP,AZGP1,FLNA,MMP9,SRC,PCNA,CFI,FIGNL1,CFB,CFL1,CRYAB |
| GO:0030141 | secretory granule | 12 | 845 | 0.7 | CEACAM6,VCL,HGF,CTSD,VWF,ITGA2B,SOD1,APP,PTX3,MMP9,EDN1,VEGFA |
| GO:0031983 | vesicle lumen | 8 | 330 | 0.94 | VCL,HGF,APOB,CTSD,VWF,APP,PTX3,VEGFA |
| GO:0031091 | platelet alpha granule | 5 | 91 | 1.29 | HGF,VWF,ITGA2B,APP,VEGFA |
| GO:0034774 | secretory granule lumen | 7 | 324 | 0.89 | VCL,HGF,CTSD,VWF,APP,PTX3,VEGFA |
| GO:0031093 | platelet alpha granule lumen | 4 | 68 | 1.32 | HGF,VWF,APP,VEGFA |
| GO:0030424 | axon | 9 | 646 | 0.7 | SERPINF1,SOD1,APP,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,CRYAB |
| GO:0009986 | cell surface | 10 | 824 | 0.64 | CEACAM6,ITGA2B,MCAM,APP,WIF1,AZGP1,CD5L,TNF,CRYAB,VEGFA |
| GO:0070161 | anchoring junction | 10 | 820 | 0.64 | VCL,ITGA2B,MCAM,APP,FGF13,FLNA,SRC,CFL1,AKT1,VEGFA |
| GO:0031012 | extracellular matrix | 8 | 527 | 0.73 | CTSD,SERPINF1,VWF,AZGP1,PTX3,MMP9,RBP3,VEGFA |
| GO:0033093 | Weibel-Palade body | 2 | 5 | 2.15 | VWF,EDN1 |
| GO:0030426 | growth cone | 5 | 186 | 0.98 | APP,FGF13,KIAA1598,FLNA,ARHGAP4 |
| GO:0034363 | intermediate-density lipoprotein particle | 2 | 6 | 2.07 | APOB,APP |
| GO:0044297 | cell body | 8 | 588 | 0.68 | APOB,SERPINF1,RPE65,SOD1,APP,KIAA1598,FLNA,CRYAB |
| GO:0045121 | membrane raft | 6 | 324 | 0.82 | VCL,SELPLG,CTSD,APP,SRC,TNF |
| GO:0072562 | blood microparticle | 4 | 115 | 1.09 | ITGA2B,CD5L,C1S,CFB |
| GO:0005911 | cell-cell junction | 7 | 490 | 0.71 | VCL,APP,FGF13,FLNA,CFL1,AKT1,VEGFA |
| GO:0005102 | signaling receptor binding | 21 | 1581 | 0.67 | HGF,C5,CCL2,SELPLG,FGF6,APOB,CRP,VWF,APP,WIF1,FGF13,FLNA,SRC,PCNA,EDN1,DKK3,TNF,CCL24,CFL1,PGF,VEGFA |
| GO:0030545 | receptor regulator activity | 12 | 536 | 0.9 | HGF,C5,CCL2,FGF6,APP,FGF13,EDN1,DKK3,TNF,CCL24,PGF,VEGFA |
| GO:0005515 | protein binding | 39 | 7026 | 0.3 | CEACAM6,VCL,HGF,C5,CCL2,SELPLG,FGF6,APOB,CRP,VWF,ITGA2B,PIK3CA,SOD1,APP,WIF1,PTX3,NEFH,FGF13,KIAA1598,UBE2I,S100A7A,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,DKK3,C1S,TNF,CCL24,EIF4G1,CFB,CFL1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0048018 | receptor ligand activity | 11 | 490 | 0.9 | HGF,C5,CCL2,FGF6,APP,FGF13,EDN1,TNF,CCL24,PGF,VEGFA |
| GO:0042802 | identical protein binding | 19 | 1896 | 0.55 | CEACAM6,HGF,CRP,VWF,ITGA2B,SOD1,APP,PTX3,FLNA,ARHGAP4,MMP9,PCNA,C1S,TNF,EIF4G1,CRYAB,PGF,AKT1,VEGFA |
| GO:0008236 | serine-type peptidase activity | 7 | 175 | 1.15 | HGF,CD5L,MMP9,CFI,C1S,CFB,RBP3 |
| GO:0044877 | protein-containing complex binding | 15 | 1216 | 0.64 | HGF,CRP,VWF,ITGA2B,APP,PTX3,NEFH,KIAA1598,FLNA,MMP9,SRC,PCNA,CFL1,CRYAB,PGF |
| GO:0004252 | serine-type endopeptidase activity | 6 | 154 | 1.14 | HGF,CD5L,MMP9,CFI,C1S,CFB |
| GO:0042056 | chemoattractant activity | 4 | 41 | 1.54 | HGF,APP,PGF,VEGFA |
| GO:0001848 | complement binding | 3 | 21 | 1.71 | CRP,PTX3,CFB |
| GO:0050750 | low-density lipoprotein particle receptor binding | 3 | 22 | 1.69 | APOB,CRP,APP |
| GO:0005125 | cytokine activity | 6 | 233 | 0.96 | C5,CCL2,EDN1,TNF,CCL24,VEGFA |
| GO:0005126 | cytokine receptor binding | 6 | 264 | 0.91 | C5,CCL2,TNF,CCL24,PGF,VEGFA |
| GO:0008083 | growth factor activity | 5 | 161 | 1.04 | HGF,FGF6,FGF13,PGF,VEGFA |
| hsa04510 | Focal adhesion | 10 | 198 | 1.25 | VCL,HGF,VWF,ITGA2B,PIK3CA,FLNA,SRC,PGF,AKT1,VEGFA |
| hsa05418 | Fluid shear stress and atherosclerosis | 9 | 130 | 1.39 | CCL2,ITGA2B,PIK3CA,MMP9,SRC,EDN1,TNF,AKT1,VEGFA |
| hsa04015 | Rap1 signaling pathway | 8 | 202 | 1.15 | HGF,FGF6,ITGA2B,PIK3CA,SRC,PGF,AKT1,VEGFA |
| hsa05205 | Proteoglycans in cancer | 8 | 196 | 1.16 | HGF,PIK3CA,FLNA,MMP9,SRC,TNF,AKT1,VEGFA |
| hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 6 | 98 | 1.34 | CCL2,PIK3CA,EDN1,TNF,AKT1,VEGFA |
| hsa04668 | TNF signaling pathway | 6 | 112 | 1.28 | CCL2,PIK3CA,MMP9,EDN1,TNF,AKT1 |
| hsa04926 | Relaxin signaling pathway | 6 | 128 | 1.22 | PIK3CA,MMP9,SRC,EDN1,AKT1,VEGFA |
| hsa05200 | Pathways in cancer | 10 | 517 | 0.84 | HGF,FGF6,ITGA2B,PIK3CA,FRAT2,MMP9,EDN1,PGF,AKT1,VEGFA |
| hsa01521 | EGFR tyrosine kinase inhibitor resistance | 5 | 78 | 1.36 | HGF,PIK3CA,SRC,AKT1,VEGFA |
| hsa04610 | Complement and coagulation cascades | 5 | 82 | 1.34 | C5,VWF,CFI,C1S,CFB |
| hsa05150 | Staphylococcus aureus infection | 5 | 86 | 1.32 | C5,SELPLG,CFI,C1S,CFB |
| hsa04151 | PI3K-Akt signaling pathway | 8 | 350 | 0.91 | HGF,FGF6,VWF,ITGA2B,PIK3CA,PGF,AKT1,VEGFA |
| hsa05161 | Hepatitis B | 6 | 159 | 1.13 | PIK3CA,MMP9,SRC,PCNA,TNF,AKT1 |
| hsa04010 | MAPK signaling pathway | 7 | 288 | 0.94 | HGF,FGF6,FLNA,TNF,PGF,AKT1,VEGFA |
| hsa04370 | VEGF signaling pathway | 4 | 57 | 1.4 | PIK3CA,SRC,AKT1,VEGFA |
| hsa04213 | Longevity regulating pathway - multiple species | 4 | 61 | 1.37 | PIK3CA,SOD1,CRYAB,AKT1 |
| hsa04611 | Platelet activation | 5 | 122 | 1.16 | VWF,ITGA2B,PIK3CA,SRC,AKT1 |
| hsa04810 | Regulation of actin cytoskeleton | 6 | 209 | 1.01 | VCL,FGF6,ITGA2B,PIK3CA,SRC,CFL1 |
| hsa05135 | Yersinia infection | 5 | 125 | 1.15 | CCL2,PIK3CA,SRC,TNF,AKT1 |
| hsa05163 | Human cytomegalovirus infection | 6 | 218 | 0.99 | CCL2,PIK3CA,SRC,TNF,AKT1,VEGFA |
| hsa04014 | Ras signaling pathway | 6 | 226 | 0.98 | HGF,FGF6,PIK3CA,PGF,AKT1,VEGFA |
| hsa04915 | Estrogen signaling pathway | 5 | 133 | 1.13 | CTSD,PIK3CA,MMP9,SRC,AKT1 |
| hsa05211 | Renal cell carcinoma | 4 | 66 | 1.33 | HGF,PIK3CA,AKT1,VEGFA |
| hsa05218 | Melanoma | 4 | 72 | 1.3 | HGF,FGF6,PIK3CA,AKT1 |
| hsa05226 | Gastric cancer | 5 | 144 | 1.09 | HGF,FGF6,PIK3CA,FRAT2,AKT1 |
| hsa05133 | Pertussis | 4 | 74 | 1.28 | C5,C1S,TNF,CFL1 |
| hsa04657 | IL-17 signaling pathway | 4 | 92 | 1.19 | CCL2,S100A7A,MMP9,TNF |
| hsa01522 | Endocrine resistance | 4 | 95 | 1.18 | PIK3CA,MMP9,SRC,AKT1 |
| hsa04062 | Chemokine signaling pathway | 5 | 186 | 0.98 | CCL2,PIK3CA,SRC,CCL24,AKT1 |
| hsa05142 | Chagas disease | 4 | 99 | 1.16 | CCL2,PIK3CA,TNF,AKT1 |
| hsa04625 | C-type lectin receptor signaling pathway | 4 | 102 | 1.14 | PIK3CA,SRC,TNF,AKT1 |
| hsa04066 | HIF-1 signaling pathway | 4 | 106 | 1.13 | PIK3CA,EDN1,AKT1,VEGFA |
| hsa05219 | Bladder cancer | 3 | 41 | 1.42 | MMP9,SRC,VEGFA |
| hsa05165 | Human papillomavirus infection | 6 | 325 | 0.82 | VWF,ITGA2B,PIK3CA,TNF,AKT1,VEGFA |
| hsa04071 | Sphingolipid signaling pathway | 4 | 116 | 1.09 | CTSD,PIK3CA,TNF,AKT1 |
| hsa05144 | Malaria | 3 | 46 | 1.37 | HGF,CCL2,TNF |
| hsa05131 | Shigellosis | 5 | 218 | 0.91 | VCL,PIK3CA,SRC,TNF,AKT1 |
| hsa05010 | Alzheimer disease | 6 | 355 | 0.78 | NDUFB4,PIK3CA,APP,FRAT2,TNF,AKT1 |
| hsa04210 | Apoptosis | 4 | 132 | 1.03 | CTSD,PIK3CA,TNF,AKT1 |
| hsa05224 | Breast cancer | 4 | 145 | 0.99 | FGF6,PIK3CA,FRAT2,AKT1 |
| hsa04932 | Non-alcoholic fatty liver disease | 4 | 148 | 0.98 | NDUFB4,PIK3CA,TNF,AKT1 |
| hsa04664 | Fc epsilon RI signaling pathway | 3 | 66 | 1.21 | PIK3CA,TNF,AKT1 |
| hsa05020 | Prion disease | 5 | 265 | 0.83 | NDUFB4,C5,PIK3CA,SOD1,TNF |
| hsa05223 | Non-small cell lung cancer | 3 | 68 | 1.2 | HGF,PIK3CA,AKT1 |
| hsa04917 | Prolactin signaling pathway | 3 | 69 | 1.19 | PIK3CA,SRC,AKT1 |
| hsa05100 | Bacterial invasion of epithelial cells | 3 | 70 | 1.18 | VCL,PIK3CA,SRC |
| hsa05206 | MicroRNAs in cancer | 4 | 160 | 0.95 | PIK3CA,UBE2I,MMP9,VEGFA |
| hsa05225 | Hepatocellular carcinoma | 4 | 160 | 0.95 | HGF,PIK3CA,FRAT2,AKT1 |
| hsa05164 | Influenza A | 4 | 165 | 0.94 | CCL2,PIK3CA,TNF,AKT1 |
| hsa05212 | Pancreatic cancer | 3 | 73 | 1.16 | PIK3CA,AKT1,VEGFA |
| hsa05152 | Tuberculosis | 4 | 168 | 0.93 | CTSD,SRC,TNF,AKT1 |
| hsa04012 | ErbB signaling pathway | 3 | 83 | 1.11 | PIK3CA,SRC,AKT1 |
| hsa05323 | Rheumatoid arthritis | 3 | 85 | 1.1 | CCL2,TNF,VEGFA |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 4 | 187 | 0.88 | PIK3CA,SRC,AKT1,VEGFA |
| hsa05410 | Hypertrophic cardiomyopathy | 3 | 89 | 1.08 | ITGA2B,EDN1,TNF |
| hsa04666 | Fc gamma R-mediated phagocytosis | 3 | 90 | 1.07 | PIK3CA,CFL1,AKT1 |
| hsa05168 | Herpes simplex virus 1 infection | 6 | 479 | 0.65 | C5,CCL2,PIK3CA,SRC,TNF,AKT1 |
| hsa05222 | Small cell lung cancer | 3 | 92 | 1.06 | ITGA2B,PIK3CA,AKT1 |
| hsa05322 | Systemic lupus erythematosus | 3 | 93 | 1.06 | C5,C1S,TNF |
| hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 3 | 96 | 1.05 | CCL2,TNF,CCL24 |
| hsa05170 | Human immunodeficiency virus 1 infection | 4 | 204 | 0.84 | PIK3CA,TNF,CFL1,AKT1 |
| hsa05215 | Prostate cancer | 3 | 96 | 1.05 | PIK3CA,MMP9,AKT1 |
| hsa05132 | Salmonella infection | 4 | 209 | 0.83 | PIK3CA,FLNA,TNF,AKT1 |
| hsa05146 | Amoebiasis | 3 | 100 | 1.03 | VCL,PIK3CA,TNF |
| hsa04620 | Toll-like receptor signaling pathway | 3 | 101 | 1.02 | PIK3CA,TNF,AKT1 |
| hsa04660 | T cell receptor signaling pathway | 3 | 101 | 1.02 | PIK3CA,TNF,AKT1 |
| hsa05014 | Amyotrophic lateral sclerosis | 5 | 352 | 0.7 | NDUFB4,SOD1,NEFH,TNF,CCS |
| hsa04931 | Insulin resistance | 3 | 107 | 1 | PIK3CA,TNF,AKT1 |
| hsa04670 | Leukocyte transendothelial migration | 3 | 109 | 0.99 | VCL,PIK3CA,MMP9 |
| hsa04919 | Thyroid hormone signaling pathway | 3 | 119 | 0.95 | PIK3CA,SRC,AKT1 |
| hsa04380 | Osteoclast differentiation | 3 | 122 | 0.94 | PIK3CA,TNF,AKT1 |
| hsa04140 | Autophagy - animal | 3 | 130 | 0.91 | CTSD,PIK3CA,AKT1 |
| hsa04973 | Carbohydrate digestion and absorption | 2 | 44 | 1.21 | PIK3CA,AKT1 |
| hsa04930 | Type II diabetes mellitus | 2 | 46 | 1.19 | PIK3CA,TNF |
| GO:0051270 | regulation of cellular component movement | 22 | 1009 | 0.89 | CEACAM6,VCL,HGF,C5,CCL2,SERPINF1,ITGA2B,MCAM,APP,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0030334 | regulation of cell migration | 20 | 865 | 0.92 | CEACAM6,VCL,HGF,C5,CCL2,SERPINF1,ITGA2B,MCAM,APP,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0050896 | response to stimulus | 49 | 8046 | 0.34 | NDUFB4,CEACAM6,VCL,HGF,C5,CCL2,SELPLG,FGF6,APOB,CTSD,SERPINF1,CRP,VWF,RPE65,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,NEFH,FGF13,KIAA1598,CD5L,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,EIF4G1,CFB,HTN3,CFL1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0030335 | positive regulation of cell migration | 15 | 522 | 1.01 | CEACAM6,HGF,ITGA2B,MCAM,APP,KIAA1598,FLNA,MMP9,SRC,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0032879 | regulation of localization | 28 | 2740 | 0.56 | CEACAM6,VCL,HGF,C5,CCL2,APOB,CTSD,SERPINF1,CRP,ITGA2B,MCAM,SOD1,APP,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,CRYAB,PGF,AKT1,VEGFA |
| GO:0060548 | negative regulation of cell death | 18 | 999 | 0.81 | CEACAM6,HGF,CCL2,SERPINF1,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,EDN1,TNF,FIGNL1,EIF4G1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0002376 | immune system process | 26 | 2481 | 0.57 | CEACAM6,VCL,C5,CCL2,SELPLG,APOB,CTSD,CRP,PIK3CA,SOD1,APP,AZGP1,PTX3,CD5L,FLNA,MMP9,SRC,EDN1,CFI,C1S,TNF,CCL24,CFB,HTN3,AKT1,VEGFA |
| GO:0002685 | regulation of leukocyte migration | 10 | 209 | 1.23 | C5,CCL2,ITGA2B,APP,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0006950 | response to stress | 30 | 3485 | 0.49 | NDUFB4,VCL,C5,CCL2,CRP,VWF,ITGA2B,PIK3CA,MCAM,SOD1,APP,PTX3,CD5L,FLNA,MMP9,SRC,PCNA,EDN1,CFI,C1S,TNF,CCL24,EIF4G1,CFB,HTN3,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0010951 | negative regulation of endopeptidase activity | 10 | 248 | 1.16 | HGF,C5,SERPINF1,APP,MMP9,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:0016477 | cell migration | 16 | 896 | 0.8 | CEACAM6,HGF,C5,CCL2,SELPLG,APOB,PIK3CA,FGF13,KIAA1598,FLNA,SRC,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0002576 | platelet degranulation | 8 | 129 | 1.34 | VCL,HGF,VWF,ITGA2B,SOD1,APP,FLNA,VEGFA |
| GO:0002684 | positive regulation of immune system process | 16 | 949 | 0.78 | C5,CCL2,CRP,ITGA2B,PIK3CA,APP,SRC,EDN1,CFI,C1S,TNF,CCL24,CFB,PGF,AKT1,VEGFA |
| GO:0040011 | locomotion | 18 | 1251 | 0.71 | CEACAM6,HGF,C5,CCL2,SELPLG,APOB,PIK3CA,APP,FGF13,KIAA1598,FLNA,SRC,TNF,CCL24,CFL1,PGF,AKT1,VEGFA |
| GO:0009653 | anatomical structure morphogenesis | 23 | 2165 | 0.58 | VCL,HGF,CCL2,FGF6,APOB,RPE65,PIK3CA,MCAM,SOD1,APP,NEFH,KIAA1598,FLNA,MMP9,SRC,EDN1,DKK3,TNF,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 7 | 85 | 1.47 | HGF,MMP9,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:0050793 | regulation of developmental process | 25 | 2648 | 0.53 | VCL,HGF,CCL2,APOB,SERPINF1,CRP,ITGA2B,PIK3CA,SOD1,APP,WIF1,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CFL1,PGF,AKT1,VEGFA |
| GO:0044093 | positive regulation of molecular function | 21 | 1842 | 0.61 | HGF,C5,CCL2,CTSD,PIK3CA,SOD1,APP,FGF13,UBE2I,ARHGAP4,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,EIF4G1,CCS,AKT1,VEGFA |
| GO:0001934 | positive regulation of protein phosphorylation | 16 | 1019 | 0.75 | HGF,C5,CCL2,PIK3CA,SOD1,APP,FGF13,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0043085 | positive regulation of catalytic activity | 19 | 1489 | 0.66 | HGF,C5,CCL2,CTSD,PIK3CA,SOD1,APP,FGF13,UBE2I,ARHGAP4,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,CCS,AKT1,VEGFA |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 9 | 216 | 1.17 | HGF,CTSD,APP,MMP9,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:0045937 | positive regulation of phosphate metabolic process | 17 | 1164 | 0.72 | HGF,C5,CCL2,PIK3CA,SOD1,APP,FGF13,MMP9,SRC,EDN1,GUCA1A,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0048583 | regulation of response to stimulus | 31 | 4114 | 0.43 | HGF,C5,CCL2,FGF6,SERPINF1,CRP,PIK3CA,SOD1,APP,WIF1,UBE2I,CD5L,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,GUCA1A,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,EIF4G1,CFB,CRYAB,PGF,AKT1,VEGFA |
| GO:0043066 | negative regulation of apoptotic process | 15 | 893 | 0.78 | CEACAM6,HGF,CCL2,PIK3CA,SOD1,FLNA,MMP9,SRC,EDN1,TNF,FIGNL1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0044419 | interspecies interaction between organisms | 21 | 1899 | 0.59 | C5,CCL2,SELPLG,APOB,CRP,APP,PTX3,UBE2I,FLNA,SRC,PCNA,EDN1,CFI,C1S,TNF,CCL24,EIF4G1,CFB,HTN3,CFL1,AKT1 |
| GO:0009605 | response to external stimulus | 23 | 2310 | 0.55 | HGF,C5,CCL2,APOB,CRP,RPE65,PIK3CA,APP,PTX3,FLNA,SRC,EDN1,CFI,C1S,TNF,CCL24,EIF4G1,CFB,HTN3,CFL1,PGF,AKT1,VEGFA |
| GO:0032501 | multicellular organismal process | 40 | 6933 | 0.31 | VCL,HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,CRP,VWF,RPE65,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,FIGNL1,EIF4G1,HTN3,CFL1,CRYAB,ARMS2,PGF,AKT1,RBP3,VEGFA |
| GO:0007166 | cell surface receptor signaling pathway | 23 | 2325 | 0.55 | HGF,C5,CCL2,FGF6,RPE65,ITGA2B,PIK3CA,SOD1,APP,WIF1,KIAA1598,FLNA,FRAT2,MMP9,SRC,EDN1,DKK3,TNF,CCL24,CFL1,PGF,AKT1,VEGFA |
| GO:2000379 | positive regulation of reactive oxygen species metabolic process | 7 | 103 | 1.38 | CRP,SOD1,APP,PTX3,EDN1,TNF,AKT1 |
| GO:0052548 | regulation of endopeptidase activity | 11 | 418 | 0.97 | HGF,C5,CTSD,SERPINF1,APP,MMP9,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:0010035 | response to inorganic substance | 12 | 538 | 0.9 | APOB,SERPINF1,SOD1,APP,MMP9,SRC,PCNA,EDN1,GUCA1A,CRYAB,CCS,AKT1 |
| GO:0031401 | positive regulation of protein modification process | 17 | 1252 | 0.68 | HGF,C5,CCL2,PIK3CA,SOD1,APP,FGF13,UBE2I,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0034097 | response to cytokine | 16 | 1101 | 0.71 | HGF,CCL2,SELPLG,APOB,PIK3CA,SOD1,APP,NEFH,MMP9,SRC,EDN1,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0050790 | regulation of catalytic activity | 23 | 2386 | 0.54 | HGF,C5,CCL2,CTSD,SERPINF1,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,ARHGAP4,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,CRYAB,CCS,AKT1,VEGFA |
| GO:0051707 | response to other organism | 17 | 1256 | 0.68 | C5,CCL2,APOB,CRP,APP,PTX3,FLNA,SRC,EDN1,CFI,C1S,TNF,CCL24,CFB,HTN3,CFL1,AKT1 |
| GO:0048518 | positive regulation of biological process | 37 | 6112 | 0.33 | CEACAM6,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,PTX3,FGF13,KIAA1598,UBE2I,CD5L,FLNA,MMP9,SRC,PCNA,EDN1,GUCA1A,CFI,C1S,TNF,CCL24,EIF4G1,CFB,CFL1,CCS,PGF,AKT1,VEGFA |
| GO:0051336 | regulation of hydrolase activity | 17 | 1284 | 0.67 | HGF,C5,CCL2,CTSD,SERPINF1,SOD1,APP,PTX3,ARHGAP4,MMP9,SRC,PCNA,TNF,CCL24,CRYAB,AKT1,VEGFA |
| GO:0051346 | negative regulation of hydrolase activity | 11 | 450 | 0.94 | HGF,C5,SERPINF1,APP,PTX3,MMP9,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:0022008 | neurogenesis | 19 | 1657 | 0.61 | VCL,HGF,CCL2,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0051347 | positive regulation of transferase activity | 13 | 705 | 0.82 | HGF,C5,PIK3CA,SOD1,APP,FGF13,UBE2I,SRC,PCNA,EDN1,TNF,AKT1,VEGFA |
| GO:0048584 | positive regulation of response to stimulus | 22 | 2257 | 0.54 | HGF,C5,CCL2,FGF6,CRP,PIK3CA,SOD1,APP,UBE2I,FLNA,MMP9,SRC,PCNA,EDN1,CFI,C1S,TNF,CCL24,CFB,PGF,AKT1,VEGFA |
| GO:0048731 | system development | 31 | 4426 | 0.4 | VCL,HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,MCAM,SOD1,APP,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,HTN3,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0070887 | cellular response to chemical stimulus | 25 | 2919 | 0.48 | HGF,C5,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FLNA,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,CFL1,CCS,PGF,AKT1,VEGFA |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 8 | 188 | 1.18 | CRP,SOD1,APP,PTX3,EDN1,TNF,CRYAB,AKT1 |
| GO:0006928 | movement of cell or subcellular component | 18 | 1501 | 0.63 | CEACAM6,HGF,C5,CCL2,SELPLG,APOB,PIK3CA,SOD1,APP,FGF13,KIAA1598,FLNA,SRC,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0045595 | regulation of cell differentiation | 20 | 1874 | 0.58 | VCL,HGF,APOB,SERPINF1,CRP,ITGA2B,SOD1,APP,WIF1,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,EDN1,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0006959 | humoral immune response | 9 | 275 | 1.07 | C5,CCL2,CRP,APP,CFI,C1S,TNF,CFB,HTN3 |
| GO:0002682 | regulation of immune system process | 18 | 1514 | 0.63 | C5,CCL2,CRP,ITGA2B,PIK3CA,SOD1,APP,CD5L,SRC,EDN1,CFI,C1S,TNF,CCL24,CFB,PGF,AKT1,VEGFA |
| GO:0010941 | regulation of cell death | 19 | 1696 | 0.6 | CEACAM6,HGF,CCL2,CTSD,SERPINF1,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,EDN1,TNF,FIGNL1,EIF4G1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0002920 | regulation of humoral immune response | 6 | 75 | 1.45 | C5,CD5L,CFI,C1S,TNF,CFB |
| GO:0000302 | response to reactive oxygen species | 8 | 198 | 1.16 | SOD1,MMP9,SRC,PCNA,EDN1,CRYAB,CCS,AKT1 |
| GO:0032147 | activation of protein kinase activity | 10 | 376 | 0.98 | HGF,C5,PIK3CA,SOD1,APP,FGF13,SRC,TNF,AKT1,VEGFA |
| GO:1902533 | positive regulation of intracellular signal transduction | 15 | 1041 | 0.71 | HGF,C5,CCL2,FGF6,PIK3CA,SOD1,APP,UBE2I,FLNA,SRC,EDN1,TNF,CCL24,AKT1,VEGFA |
| GO:0048699 | generation of neurons | 18 | 1551 | 0.62 | VCL,HGF,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0006979 | response to oxidative stress | 10 | 393 | 0.96 | NDUFB4,SOD1,APP,MMP9,SRC,PCNA,EDN1,CRYAB,CCS,AKT1 |
| GO:1901701 | cellular response to oxygen-containing compound | 15 | 1055 | 0.7 | CCL2,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,PCNA,EDN1,TNF,CCS,AKT1 |
| GO:0002687 | positive regulation of leukocyte migration | 7 | 144 | 1.24 | ITGA2B,APP,EDN1,TNF,CCL24,PGF,VEGFA |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 7 | 146 | 1.23 | HGF,PIK3CA,APP,TNF,EIF4G1,AKT1,VEGFA |
| GO:0045429 | positive regulation of nitric oxide biosynthetic process | 5 | 44 | 1.61 | APP,PTX3,EDN1,TNF,AKT1 |
| GO:0050900 | leukocyte migration | 9 | 316 | 1.01 | CEACAM6,CCL2,SELPLG,APOB,PIK3CA,SRC,TNF,CCL24,VEGFA |
| GO:0032270 | positive regulation of cellular protein metabolic process | 18 | 1635 | 0.59 | HGF,C5,CCL2,CTSD,PIK3CA,SOD1,APP,FGF13,UBE2I,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0060284 | regulation of cell development | 14 | 956 | 0.72 | VCL,HGF,SERPINF1,APP,FGF13,KIAA1598,FLNA,ARHGAP4,EDN1,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0007275 | multicellular organism development | 32 | 5023 | 0.36 | VCL,HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,MCAM,SOD1,APP,WIF1,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,HTN3,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0002252 | immune effector process | 14 | 969 | 0.71 | CEACAM6,VCL,C5,CTSD,CRP,PIK3CA,APP,PTX3,FLNA,MMP9,SRC,CFI,C1S,CFB |
| GO:0006952 | defense response | 16 | 1296 | 0.64 | C5,CCL2,CRP,APP,PTX3,CD5L,FLNA,EDN1,CFI,C1S,TNF,CCL24,EIF4G1,CFB,HTN3,AKT1 |
| GO:0045860 | positive regulation of protein kinase activity | 11 | 550 | 0.85 | HGF,C5,PIK3CA,SOD1,APP,FGF13,SRC,EDN1,TNF,AKT1,VEGFA |
| GO:0048638 | regulation of developmental growth | 9 | 333 | 0.98 | PIK3CA,SOD1,APP,FGF13,KIAA1598,ARHGAP4,EDN1,AKT1,VEGFA |
| GO:0045055 | regulated exocytosis | 12 | 697 | 0.79 | CEACAM6,VCL,HGF,CTSD,VWF,ITGA2B,SOD1,APP,PTX3,FLNA,MMP9,VEGFA |
| GO:2000026 | regulation of multicellular organismal development | 20 | 2096 | 0.53 | VCL,HGF,SERPINF1,ITGA2B,SOD1,APP,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CFL1,PGF,AKT1,VEGFA |
| GO:0006956 | complement activation | 5 | 54 | 1.52 | C5,CRP,CFI,C1S,CFB |
| GO:0071345 | cellular response to cytokine stimulus | 14 | 1013 | 0.69 | HGF,CCL2,SELPLG,APOB,PIK3CA,SOD1,NEFH,MMP9,EDN1,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0071902 | positive regulation of protein serine/threonine kinase activity | 9 | 348 | 0.96 | HGF,C5,SOD1,APP,SRC,EDN1,TNF,AKT1,VEGFA |
| GO:0048871 | multicellular organismal homeostasis | 9 | 352 | 0.96 | VCL,RPE65,PIK3CA,SOD1,AZGP1,SRC,EIF4G1,ARMS2,VEGFA |
| GO:0065008 | regulation of biological quality | 28 | 4042 | 0.39 | VCL,CCL2,APOB,SERPINF1,CRP,VWF,RPE65,ITGA2B,PIK3CA,SOD1,APP,AZGP1,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,PCNA,EDN1,DKK3,TNF,CCL24,EIF4G1,CFL1,CRYAB,ARMS2,AKT1,VEGFA |
| GO:0003008 | system process | 19 | 1942 | 0.54 | VCL,CCL2,SERPINF1,CRP,RPE65,PIK3CA,MCAM,SOD1,APP,AZGP1,FGF13,SRC,EDN1,GUCA1A,TNF,CRYAB,AKT1,RBP3,VEGFA |
| GO:0030449 | regulation of complement activation | 5 | 56 | 1.5 | C5,CD5L,CFI,C1S,CFB |
| GO:0042981 | regulation of apoptotic process | 17 | 1550 | 0.59 | CEACAM6,HGF,CCL2,CTSD,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,EDN1,TNF,FIGNL1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0071310 | cellular response to organic substance | 21 | 2369 | 0.5 | HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FLNA,MMP9,SRC,EDN1,TNF,CCL24,CFL1,PGF,AKT1,VEGFA |
| GO:0043406 | positive regulation of MAP kinase activity | 8 | 265 | 1.03 | HGF,C5,SOD1,APP,SRC,EDN1,TNF,VEGFA |
| GO:1901700 | response to oxygen-containing compound | 17 | 1567 | 0.59 | CCL2,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,PCNA,EDN1,TNF,CFL1,CRYAB,CCS,AKT1 |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 6 | 112 | 1.28 | PIK3CA,APP,TNF,EIF4G1,AKT1,VEGFA |
| GO:0051716 | cellular response to stimulus | 36 | 6489 | 0.3 | CEACAM6,HGF,C5,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,ITGA2B,PIK3CA,SOD1,APP,WIF1,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,CCL24,FIGNL1,EIF4G1,CFL1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0098542 | defense response to other organism | 13 | 900 | 0.71 | C5,CCL2,CRP,APP,PTX3,FLNA,EDN1,CFI,C1S,TNF,CCL24,CFB,HTN3 |
| GO:0048522 | positive regulation of cellular process | 33 | 5579 | 0.32 | CEACAM6,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,PTX3,FGF13,KIAA1598,UBE2I,CD5L,FLNA,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,EIF4G1,CFL1,PGF,AKT1,VEGFA |
| GO:0001775 | cell activation | 14 | 1075 | 0.67 | CEACAM6,VCL,SELPLG,CTSD,VWF,ITGA2B,PIK3CA,APP,PTX3,FLNA,MMP9,SRC,EDN1,TNF |
| GO:0016192 | vesicle-mediated transport | 18 | 1805 | 0.55 | CEACAM6,VCL,HGF,APOB,CTSD,CRP,VWF,ITGA2B,PIK3CA,SOD1,APP,PTX3,CD5L,FLNA,MMP9,SRC,CFI,VEGFA |
| GO:1902531 | regulation of intracellular signal transduction | 18 | 1807 | 0.55 | HGF,C5,CCL2,FGF6,PIK3CA,SOD1,APP,UBE2I,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,FIGNL1,AKT1,VEGFA |
| GO:0071248 | cellular response to metal ion | 7 | 193 | 1.11 | SERPINF1,SOD1,APP,MMP9,EDN1,GUCA1A,AKT1 |
| GO:0022603 | regulation of anatomical structure morphogenesis | 14 | 1095 | 0.66 | HGF,CCL2,SERPINF1,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,EDN1,TNF,CCL24,CFL1,PGF,VEGFA |
| GO:0051248 | negative regulation of protein metabolic process | 14 | 1096 | 0.66 | HGF,C5,SERPINF1,APP,PTX3,FLNA,MMP9,SRC,EDN1,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0002688 | regulation of leukocyte chemotaxis | 6 | 124 | 1.24 | C5,CCL2,APP,EDN1,PGF,VEGFA |
| GO:0030154 | cell differentiation | 26 | 3702 | 0.4 | VCL,HGF,CCL2,FGF6,SERPINF1,RPE65,PIK3CA,SOD1,APP,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,TNF,FIGNL1,EIF4G1,CFL1,PGF,AKT1,VEGFA |
| GO:0048513 | animal organ development | 24 | 3197 | 0.43 | HGF,CCL2,SELPLG,FGF6,SERPINF1,RPE65,PIK3CA,SOD1,APP,PTX3,FGF13,FLNA,MMP9,SRC,PCNA,EDN1,DKK3,TNF,HTN3,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0090066 | regulation of anatomical structure size | 10 | 516 | 0.84 | CRP,SOD1,FGF13,KIAA1598,ARHGAP4,EDN1,CCL24,CFL1,AKT1,VEGFA |
| GO:0035239 | tube morphogenesis | 11 | 656 | 0.78 | CCL2,FGF6,APOB,PIK3CA,MCAM,SRC,EDN1,CFL1,PGF,AKT1,VEGFA |
| GO:0048514 | blood vessel morphogenesis | 9 | 410 | 0.89 | CCL2,FGF6,APOB,PIK3CA,MCAM,EDN1,PGF,AKT1,VEGFA |
| GO:0048732 | gland development | 9 | 410 | 0.89 | HGF,PIK3CA,SOD1,SRC,PCNA,DKK3,TNF,AKT1,VEGFA |
| GO:0010033 | response to organic substance | 23 | 3011 | 0.43 | HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FLNA,MMP9,SRC,PCNA,EDN1,TNF,CCL24,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0034614 | cellular response to reactive oxygen species | 6 | 133 | 1.21 | SOD1,MMP9,SRC,PCNA,CCS,AKT1 |
| GO:1901215 | negative regulation of neuron death | 7 | 211 | 1.07 | CCL2,SERPINF1,PIK3CA,SOD1,APP,EIF4G1,AKT1 |
| GO:0001936 | regulation of endothelial cell proliferation | 6 | 134 | 1.2 | CCL2,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0007165 | signal transduction | 30 | 4876 | 0.34 | CEACAM6,HGF,C5,CCL2,FGF6,APOB,RPE65,ITGA2B,PIK3CA,SOD1,APP,WIF1,FGF13,KIAA1598,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,CCL24,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0032940 | secretion by cell | 13 | 979 | 0.67 | CEACAM6,VCL,HGF,CTSD,VWF,ITGA2B,SOD1,APP,PTX3,FLNA,MMP9,EDN1,VEGFA |
| GO:0040008 | regulation of growth | 11 | 676 | 0.76 | PIK3CA,SOD1,APP,FGF13,KIAA1598,ARHGAP4,EDN1,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0030168 | platelet activation | 6 | 135 | 1.2 | VCL,VWF,ITGA2B,PIK3CA,FLNA,SRC |
| GO:0043410 | positive regulation of MAPK cascade | 10 | 543 | 0.82 | HGF,C5,CCL2,SOD1,APP,SRC,EDN1,TNF,CCL24,VEGFA |
| GO:0050767 | regulation of neurogenesis | 12 | 828 | 0.71 | HGF,SERPINF1,APP,FGF13,KIAA1598,FLNA,ARHGAP4,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0001525 | angiogenesis | 8 | 315 | 0.96 | CCL2,FGF6,PIK3CA,MCAM,EDN1,PGF,AKT1,VEGFA |
| GO:0001894 | tissue homeostasis | 7 | 219 | 1.06 | VCL,RPE65,SOD1,AZGP1,SRC,ARMS2,VEGFA |
| GO:1901214 | regulation of neuron death | 8 | 317 | 0.95 | CCL2,SERPINF1,PIK3CA,SOD1,APP,TNF,EIF4G1,AKT1 |
| GO:0007399 | nervous system development | 20 | 2371 | 0.48 | VCL,HGF,CCL2,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0051246 | regulation of protein metabolic process | 22 | 2828 | 0.44 | HGF,C5,CCL2,CTSD,SERPINF1,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,FLNA,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CRYAB,PGF,AKT1,VEGFA |
| GO:0032502 | developmental process | 33 | 5841 | 0.3 | VCL,HGF,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,MCAM,SOD1,APP,WIF1,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,DKK3,TNF,FIGNL1,EIF4G1,HTN3,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0032101 | regulation of response to external stimulus | 13 | 1013 | 0.66 | HGF,C5,CCL2,SERPINF1,SOD1,APP,SRC,EDN1,GUCA1A,TNF,CCL24,PGF,VEGFA |
| GO:0035295 | tube development | 12 | 851 | 0.7 | CCL2,FGF6,APOB,PIK3CA,MCAM,SRC,EDN1,TNF,CFL1,PGF,AKT1,VEGFA |
| GO:0051896 | regulation of protein kinase B signaling | 7 | 226 | 1.04 | HGF,FGF6,PIK3CA,APP,SRC,TNF,AKT1 |
| GO:0071495 | cellular response to endogenous stimulus | 14 | 1181 | 0.63 | CCL2,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,FLNA,SRC,EDN1,TNF,PGF,AKT1 |
| GO:0010632 | regulation of epithelial cell migration | 7 | 227 | 1.04 | SERPINF1,MMP9,SRC,EDN1,TNF,AKT1,VEGFA |
| GO:1900407 | regulation of cellular response to oxidative stress | 5 | 81 | 1.34 | HGF,SOD1,APP,TNF,AKT1 |
| GO:0090322 | regulation of superoxide metabolic process | 4 | 36 | 1.6 | CRP,SOD1,APP,TNF |
| GO:0051094 | positive regulation of developmental process | 15 | 1389 | 0.58 | HGF,APOB,SERPINF1,APP,WIF1,KIAA1598,FLNA,SRC,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0006955 | immune response | 16 | 1588 | 0.55 | CEACAM6,VCL,C5,CCL2,CTSD,CRP,APP,PTX3,MMP9,EDN1,CFI,C1S,TNF,CCL24,CFB,HTN3 |
| GO:0007154 | cell communication | 31 | 5320 | 0.32 | CEACAM6,HGF,C5,CCL2,FGF6,APOB,RPE65,ITGA2B,PIK3CA,SOD1,APP,WIF1,FGF13,KIAA1598,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,CCL24,EIF4G1,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0043408 | regulation of MAPK cascade | 11 | 725 | 0.73 | HGF,C5,CCL2,SOD1,APP,SRC,EDN1,TNF,CCL24,AKT1,VEGFA |
| GO:0006958 | complement activation, classical pathway | 4 | 38 | 1.57 | C5,CRP,CFI,C1S |
| GO:0043491 | protein kinase B signaling | 4 | 38 | 1.57 | CCL2,PIK3CA,TNF,AKT1 |
| GO:0080135 | regulation of cellular response to stress | 11 | 739 | 0.72 | HGF,SOD1,APP,PCNA,EDN1,TNF,FIGNL1,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0014070 | response to organic cyclic compound | 12 | 911 | 0.67 | CCL2,APOB,SERPINF1,SOD1,APP,FLNA,SRC,PCNA,EDN1,TNF,CRYAB,AKT1 |
| GO:0009719 | response to endogenous stimulus | 15 | 1447 | 0.57 | CCL2,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,FLNA,SRC,PCNA,EDN1,TNF,PGF,AKT1 |
| GO:0042127 | regulation of cell population proliferation | 16 | 1642 | 0.54 | CEACAM6,CCL2,FGF6,SERPINF1,CRP,APP,AZGP1,FLNA,MMP9,SRC,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0051239 | regulation of multicellular organismal process | 23 | 3227 | 0.4 | VCL,HGF,C5,SERPINF1,CRP,ITGA2B,PIK3CA,SOD1,APP,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CFL1,PGF,AKT1,VEGFA |
| GO:0007155 | cell adhesion | 12 | 925 | 0.66 | CEACAM6,VCL,CCL2,SELPLG,VWF,ITGA2B,MCAM,APP,AZGP1,FLNA,SRC,TNF |
| GO:0009967 | positive regulation of signal transduction | 16 | 1654 | 0.54 | HGF,C5,CCL2,FGF6,PIK3CA,SOD1,APP,UBE2I,FLNA,MMP9,SRC,EDN1,TNF,CCL24,AKT1,VEGFA |
| GO:0010038 | response to metal ion | 8 | 367 | 0.89 | SERPINF1,SOD1,APP,MMP9,PCNA,EDN1,GUCA1A,AKT1 |
| GO:0048523 | negative regulation of cellular process | 29 | 4874 | 0.33 | CEACAM6,VCL,HGF,C5,CCL2,SERPINF1,CRP,PIK3CA,SOD1,APP,WIF1,AZGP1,PTX3,FGF13,UBE2I,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,DKK3,TNF,FIGNL1,EIF4G1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0030336 | negative regulation of cell migration | 7 | 262 | 0.98 | VCL,C5,CCL2,SERPINF1,ARHGAP4,TNF,AKT1 |
| GO:0051897 | positive regulation of protein kinase B signaling | 6 | 170 | 1.1 | HGF,FGF6,PIK3CA,APP,SRC,TNF |
| GO:0071363 | cellular response to growth factor stimulus | 9 | 494 | 0.81 | HGF,CCL2,FGF6,APP,SRC,EDN1,PGF,AKT1,VEGFA |
| GO:0042592 | homeostatic process | 16 | 1676 | 0.53 | VCL,CCL2,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,AZGP1,SRC,PCNA,EDN1,EIF4G1,ARMS2,AKT1,VEGFA |
| GO:0022604 | regulation of cell morphogenesis | 9 | 498 | 0.81 | CCL2,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,CCL24,CFL1,VEGFA |
| GO:0042221 | response to chemical | 27 | 4333 | 0.35 | HGF,C5,CCL2,SELPLG,FGF6,APOB,SERPINF1,RPE65,PIK3CA,SOD1,APP,AZGP1,NEFH,FLNA,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,CFL1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0007010 | cytoskeleton organization | 13 | 1126 | 0.61 | CCL2,SOD1,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,SRC,TNF,CCL24,FIGNL1,CFL1,CRYAB |
| GO:0060249 | anatomical structure homeostasis | 8 | 380 | 0.87 | VCL,RPE65,SOD1,AZGP1,SRC,PCNA,ARMS2,VEGFA |
| GO:0032535 | regulation of cellular component size | 8 | 383 | 0.87 | FGF13,KIAA1598,ARHGAP4,EDN1,CCL24,CFL1,AKT1,VEGFA |
| GO:0006954 | inflammatory response | 9 | 515 | 0.79 | C5,CCL2,CRP,APP,PTX3,CD5L,TNF,CCL24,AKT1 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 9 | 518 | 0.79 | HGF,FGF6,RPE65,PIK3CA,MMP9,SRC,PGF,AKT1,VEGFA |
| GO:0008361 | regulation of cell size | 6 | 183 | 1.07 | FGF13,KIAA1598,ARHGAP4,EDN1,AKT1,VEGFA |
| GO:0009628 | response to abiotic stimulus | 13 | 1147 | 0.61 | SERPINF1,RPE65,SOD1,APP,SRC,PCNA,EDN1,TNF,FIGNL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0003018 | vascular process in circulatory system | 6 | 185 | 1.06 | CRP,SOD1,SRC,EDN1,AKT1,VEGFA |
| GO:0010243 | response to organonitrogen compound | 12 | 987 | 0.64 | RPE65,PIK3CA,SOD1,APP,FLNA,MMP9,SRC,PCNA,EDN1,TNF,CFL1,AKT1 |
| GO:0044092 | negative regulation of molecular function | 13 | 1163 | 0.6 | HGF,C5,SERPINF1,APP,PTX3,FLNA,MMP9,SRC,DKK3,TNF,CRYAB,AKT1,VEGFA |
| GO:0045664 | regulation of neuron differentiation | 10 | 665 | 0.73 | HGF,SERPINF1,APP,FGF13,KIAA1598,ARHGAP4,EIF4G1,CFL1,AKT1,VEGFA |
| GO:0051179 | localization | 31 | 5591 | 0.3 | CEACAM6,VCL,HGF,C5,CCL2,SELPLG,APOB,CTSD,CRP,VWF,ITGA2B,PIK3CA,SOD1,APP,AZGP1,PTX3,FGF13,KIAA1598,CD5L,FLNA,MMP9,SRC,EDN1,CFI,TNF,CCL24,CFL1,CCS,AKT1,SLC25A16,VEGFA |
| GO:1903140 | regulation of establishment of endothelial barrier | 3 | 15 | 1.85 | VCL,TNF,VEGFA |
| GO:0009611 | response to wounding | 9 | 532 | 0.78 | VCL,VWF,ITGA2B,PIK3CA,MCAM,SOD1,FLNA,SRC,VEGFA |
| GO:0045597 | positive regulation of cell differentiation | 12 | 993 | 0.63 | HGF,APOB,SERPINF1,APP,WIF1,KIAA1598,FLNA,EDN1,TNF,EIF4G1,AKT1,VEGFA |
| GO:0001541 | ovarian follicle development | 4 | 53 | 1.43 | SOD1,PTX3,SRC,VEGFA |
| GO:0002573 | myeloid leukocyte differentiation | 5 | 113 | 1.2 | APP,MMP9,SRC,TNF,VEGFA |
| GO:0019221 | cytokine-mediated signaling pathway | 10 | 678 | 0.72 | HGF,CCL2,PIK3CA,SOD1,MMP9,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0051240 | positive regulation of multicellular organismal process | 16 | 1770 | 0.51 | HGF,C5,SERPINF1,SOD1,APP,KIAA1598,FLNA,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0071407 | cellular response to organic cyclic compound | 9 | 537 | 0.78 | CCL2,SERPINF1,SOD1,APP,FLNA,SRC,EDN1,TNF,AKT1 |
| GO:0006935 | chemotaxis | 9 | 545 | 0.77 | HGF,C5,CCL2,PIK3CA,APP,SRC,CCL24,PGF,VEGFA |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 10 | 687 | 0.71 | HGF,SERPINF1,APP,FGF13,KIAA1598,ARHGAP4,SRC,CFL1,AKT1,VEGFA |
| GO:0046890 | regulation of lipid biosynthetic process | 6 | 197 | 1.03 | APOB,SOD1,APP,DKK3,TNF,AKT1 |
| GO:1901888 | regulation of cell junction assembly | 6 | 199 | 1.03 | VCL,APP,SRC,TNF,EIF4G1,VEGFA |
| GO:0032268 | regulation of cellular protein metabolic process | 20 | 2693 | 0.42 | HGF,C5,CCL2,CTSD,SERPINF1,PIK3CA,SOD1,APP,FGF13,UBE2I,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CRYAB,PGF,AKT1,VEGFA |
| GO:0060688 | regulation of morphogenesis of a branching structure | 4 | 56 | 1.41 | HGF,TNF,PGF,VEGFA |
| GO:0001558 | regulation of cell growth | 8 | 423 | 0.83 | FGF13,KIAA1598,ARHGAP4,EDN1,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0010720 | positive regulation of cell development | 9 | 556 | 0.76 | HGF,SERPINF1,APP,KIAA1598,FLNA,EDN1,TNF,EIF4G1,VEGFA |
| GO:0022414 | reproductive process | 14 | 1400 | 0.55 | APOB,SERPINF1,SOD1,APP,PTX3,FLNA,MMP9,SRC,PCNA,EDN1,FIGNL1,PGF,AKT1,VEGFA |
| GO:0045087 | innate immune response | 10 | 703 | 0.7 | C5,CCL2,CRP,APP,PTX3,EDN1,CFI,C1S,CCL24,CFB |
| GO:0045785 | positive regulation of cell adhesion | 8 | 423 | 0.83 | CEACAM6,CCL2,PIK3CA,FLNA,SRC,TNF,AKT1,VEGFA |
| GO:0051130 | positive regulation of cellular component organization | 13 | 1209 | 0.58 | HGF,SERPINF1,APP,KIAA1598,FLNA,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CFL1,VEGFA |
| GO:0051353 | positive regulation of oxidoreductase activity | 4 | 57 | 1.4 | EDN1,TNF,CCS,AKT1 |
| GO:2000811 | negative regulation of anoikis | 3 | 18 | 1.77 | CEACAM6,PIK3CA,SRC |
| GO:0000904 | cell morphogenesis involved in differentiation | 9 | 566 | 0.75 | VCL,PIK3CA,SOD1,APP,NEFH,KIAA1598,FLNA,SRC,VEGFA |
| GO:0032269 | negative regulation of cellular protein metabolic process | 12 | 1043 | 0.61 | HGF,C5,SERPINF1,APP,MMP9,SRC,EDN1,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0071398 | cellular response to fatty acid | 4 | 58 | 1.39 | APOB,SRC,EDN1,AKT1 |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 6 | 209 | 1.01 | CCL2,APP,SRC,TNF,CCL24,VEGFA |
| GO:0048468 | cell development | 15 | 1629 | 0.52 | VCL,RPE65,PIK3CA,SOD1,APP,PTX3,NEFH,KIAA1598,FLNA,SRC,EDN1,TNF,CFL1,AKT1,VEGFA |
| GO:0000902 | cell morphogenesis | 10 | 726 | 0.69 | VCL,HGF,PIK3CA,SOD1,APP,NEFH,KIAA1598,FLNA,SRC,VEGFA |
| GO:0042060 | wound healing | 8 | 439 | 0.81 | VCL,VWF,ITGA2B,PIK3CA,MCAM,FLNA,SRC,VEGFA |
| GO:0080134 | regulation of response to stress | 14 | 1437 | 0.54 | HGF,SERPINF1,SOD1,APP,SRC,PCNA,EDN1,TNF,CCL24,FIGNL1,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0032930 | positive regulation of superoxide anion generation | 3 | 20 | 1.73 | CRP,SOD1,APP |
| GO:0046686 | response to cadmium ion | 4 | 63 | 1.35 | SOD1,MMP9,PCNA,AKT1 |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | 8 | 445 | 0.81 | VCL,PIK3CA,SOD1,APP,NEFH,KIAA1598,SRC,VEGFA |
| GO:0065007 | biological regulation | 48 | 12171 | 0.15 | CEACAM6,VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,VWF,RPE65,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,NEFH,FGF13,KIAA1598,UBE2I,CD5L,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,EIF4G1,CFB,CFL1,CRYAB,CCS,ARMS2,PGF,AKT1,VEGFA |
| GO:0065009 | regulation of molecular function | 28 | 4913 | 0.31 | HGF,C5,CCL2,FGF6,CTSD,SERPINF1,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,FLNA,ARHGAP4,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,CCL24,EIF4G1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:1900409 | positive regulation of cellular response to oxidative stress | 3 | 20 | 1.73 | SOD1,APP,TNF |
| GO:0001101 | response to acid chemical | 5 | 131 | 1.13 | PCNA,EDN1,TNF,CFL1,VEGFA |
| GO:0062012 | regulation of small molecule metabolic process | 8 | 449 | 0.8 | APOB,SOD1,APP,SRC,GUCA1A,DKK3,TNF,AKT1 |
| GO:0071417 | cellular response to organonitrogen compound | 9 | 590 | 0.73 | RPE65,PIK3CA,SOD1,APP,FLNA,SRC,EDN1,TNF,AKT1 |
| GO:0042698 | ovulation cycle | 4 | 66 | 1.33 | SERPINF1,PTX3,SRC,PCNA |
| GO:0050766 | positive regulation of phagocytosis | 4 | 66 | 1.33 | CCL2,SOD1,PTX3,TNF |
| GO:1903201 | regulation of oxidative stress-induced cell death | 4 | 67 | 1.33 | HGF,SOD1,APP,AKT1 |
| GO:0032872 | regulation of stress-activated MAPK cascade | 6 | 228 | 0.97 | HGF,APP,EDN1,TNF,AKT1,VEGFA |
| GO:0050678 | regulation of epithelial cell proliferation | 7 | 339 | 0.87 | CCL2,SERPINF1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 4 | 69 | 1.31 | PIK3CA,SRC,PGF,VEGFA |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 6 | 232 | 0.96 | HGF,MMP9,SRC,TNF,FIGNL1,AKT1 |
| GO:2000573 | positive regulation of DNA biosynthetic process | 4 | 70 | 1.31 | HGF,SRC,PCNA,VEGFA |
| GO:0009893 | positive regulation of metabolic process | 24 | 3893 | 0.34 | HGF,C5,CCL2,APOB,CTSD,CRP,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,EIF4G1,CCS,PGF,AKT1,VEGFA |
| GO:0009966 | regulation of signal transduction | 21 | 3107 | 0.38 | HGF,C5,CCL2,FGF6,PIK3CA,SOD1,APP,WIF1,UBE2I,FLNA,ARHGAP4,MMP9,SRC,EDN1,GUCA1A,DKK3,TNF,CCL24,FIGNL1,AKT1,VEGFA |
| GO:0035556 | intracellular signal transduction | 15 | 1712 | 0.49 | HGF,CCL2,FGF6,PIK3CA,APP,FGF13,KIAA1598,ARHGAP4,SRC,PCNA,EDN1,TNF,CFL1,CRYAB,AKT1 |
| GO:0050769 | positive regulation of neurogenesis | 8 | 479 | 0.77 | HGF,SERPINF1,APP,KIAA1598,FLNA,TNF,EIF4G1,VEGFA |
| GO:0062013 | positive regulation of small molecule metabolic process | 5 | 144 | 1.09 | APP,SRC,GUCA1A,TNF,AKT1 |
| GO:0097435 | supramolecular fiber organization | 8 | 480 | 0.77 | APP,NEFH,FGF13,KIAA1598,FLNA,SRC,FIGNL1,CFL1 |
| GO:0006468 | protein phosphorylation | 11 | 952 | 0.61 | HGF,CCL2,FGF6,PIK3CA,APP,FGF13,SRC,TNF,CFL1,CRYAB,AKT1 |
| GO:0051128 | regulation of cellular component organization | 18 | 2402 | 0.43 | VCL,HGF,SERPINF1,APP,FGF13,KIAA1598,FLNA,ARHGAP4,MMP9,SRC,EDN1,TNF,CCL24,EIF4G1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0010634 | positive regulation of epithelial cell migration | 5 | 147 | 1.08 | MMP9,SRC,EDN1,AKT1,VEGFA |
| GO:0001895 | retina homeostasis | 4 | 74 | 1.28 | RPE65,SOD1,AZGP1,ARMS2 |
| GO:0009617 | response to bacterium | 9 | 634 | 0.7 | CCL2,APOB,CRP,APP,SRC,EDN1,TNF,HTN3,AKT1 |
| GO:0010638 | positive regulation of organelle organization | 9 | 633 | 0.7 | APP,FLNA,MMP9,SRC,EDN1,TNF,CCL24,CFL1,VEGFA |
| GO:0050789 | regulation of biological process | 46 | 11475 | 0.15 | CEACAM6,VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,RPE65,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,NEFH,FGF13,KIAA1598,UBE2I,CD5L,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,CFI,DKK3,C1S,TNF,CCL24,FIGNL1,EIF4G1,CFB,CFL1,CRYAB,CCS,PGF,AKT1,VEGFA |
| GO:0030225 | macrophage differentiation | 3 | 26 | 1.61 | APP,MMP9,VEGFA |
| GO:0031325 | positive regulation of cellular metabolic process | 22 | 3413 | 0.36 | HGF,C5,CCL2,CTSD,CRP,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0051052 | regulation of DNA metabolic process | 7 | 360 | 0.84 | HGF,PIK3CA,SRC,PCNA,FIGNL1,AKT1,VEGFA |
| GO:0071356 | cellular response to tumor necrosis factor | 6 | 245 | 0.94 | CCL2,APOB,EDN1,TNF,CCL24,AKT1 |
| GO:1902930 | regulation of alcohol biosynthetic process | 4 | 75 | 1.28 | APOB,SOD1,DKK3,TNF |
| GO:0002443 | leukocyte mediated immunity | 9 | 641 | 0.7 | CEACAM6,VCL,C5,CTSD,CRP,PTX3,MMP9,CFI,C1S |
| GO:0009888 | tissue development | 15 | 1760 | 0.48 | VCL,HGF,FGF6,PIK3CA,SOD1,FLNA,MMP9,SRC,PCNA,EDN1,HTN3,CFL1,PGF,AKT1,VEGFA |
| GO:1905952 | regulation of lipid localization | 5 | 151 | 1.07 | APOB,CRP,EDN1,TNF,AKT1 |
| GO:0019538 | protein metabolic process | 25 | 4251 | 0.32 | HGF,CCL2,FGF6,APOB,CTSD,VWF,PIK3CA,APP,FGF13,UBE2I,CD5L,FLNA,MMP9,SRC,PCNA,CFI,C1S,TNF,EIF4G1,CFB,CFL1,CRYAB,CCS,AKT1,RBP3 |
| GO:0048609 | multicellular organismal reproductive process | 10 | 807 | 0.64 | APOB,SERPINF1,SOD1,APP,PTX3,SRC,PCNA,EDN1,FIGNL1,AKT1 |
| GO:0032102 | negative regulation of response to external stimulus | 7 | 367 | 0.83 | HGF,C5,CCL2,SERPINF1,SOD1,EDN1,TNF |
| GO:1902903 | regulation of supramolecular fiber organization | 7 | 368 | 0.83 | APP,FGF13,FLNA,EDN1,CCL24,CFL1,CRYAB |
| GO:0000187 | activation of MAPK activity | 5 | 157 | 1.05 | HGF,C5,SOD1,APP,TNF |
| GO:0050878 | regulation of body fluid levels | 8 | 509 | 0.75 | VCL,VWF,ITGA2B,PIK3CA,FLNA,SRC,EDN1,VEGFA |
| GO:0010975 | regulation of neuron projection development | 8 | 510 | 0.75 | HGF,SERPINF1,FGF13,KIAA1598,ARHGAP4,CFL1,AKT1,VEGFA |
| GO:0044788 | modulation by host of viral process | 3 | 29 | 1.57 | CRP,PTX3,CFL1 |
| GO:0010507 | negative regulation of autophagy | 4 | 82 | 1.24 | HGF,PIK3CA,EIF4G1,AKT1 |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 21 | 3239 | 0.36 | HGF,C5,CCL2,CTSD,PIK3CA,SOD1,APP,PTX3,FGF13,UBE2I,MMP9,SRC,PCNA,EDN1,GUCA1A,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0007409 | axonogenesis | 7 | 384 | 0.81 | VCL,PIK3CA,APP,NEFH,KIAA1598,SRC,VEGFA |
| GO:0002253 | activation of immune response | 7 | 385 | 0.81 | C5,CRP,PIK3CA,SRC,CFI,C1S,CFB |
| GO:0010594 | regulation of endothelial cell migration | 5 | 164 | 1.04 | SERPINF1,EDN1,TNF,AKT1,VEGFA |
| GO:0031960 | response to corticosteroid | 5 | 164 | 1.04 | SERPINF1,SRC,PCNA,EDN1,TNF |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 5 | 164 | 1.04 | SOD1,MMP9,SRC,FIGNL1,AKT1 |
| GO:0009725 | response to hormone | 10 | 849 | 0.62 | APOB,SERPINF1,RPE65,PIK3CA,SRC,PCNA,EDN1,TNF,PGF,AKT1 |
| GO:0008015 | blood circulation | 7 | 394 | 0.8 | CRP,PIK3CA,SOD1,SRC,EDN1,AKT1,VEGFA |
| GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | 4 | 87 | 1.21 | HGF,PIK3CA,SRC,TNF |
| GO:0022409 | positive regulation of cell-cell adhesion | 6 | 272 | 0.89 | CEACAM6,CCL2,PIK3CA,SRC,TNF,AKT1 |
| GO:0007568 | aging | 6 | 274 | 0.89 | SERPINF1,SOD1,APP,EDN1,CRYAB,AKT1 |
| GO:0048661 | positive regulation of smooth muscle cell proliferation | 4 | 88 | 1.21 | MMP9,EDN1,TNF,AKT1 |
| GO:0030307 | positive regulation of cell growth | 5 | 171 | 1.02 | KIAA1598,EDN1,EIF4G1,AKT1,VEGFA |
| GO:0048585 | negative regulation of response to stimulus | 14 | 1636 | 0.48 | HGF,C5,CCL2,SERPINF1,SOD1,APP,WIF1,MMP9,SRC,EDN1,DKK3,TNF,FIGNL1,AKT1 |
| GO:0050810 | regulation of steroid biosynthetic process | 4 | 89 | 1.2 | APOB,SOD1,DKK3,TNF |
| GO:0034694 | response to prostaglandin | 3 | 33 | 1.51 | APOB,EDN1,AKT1 |
| GO:0044403 | symbiotic process | 10 | 865 | 0.61 | CCL2,SELPLG,CRP,PTX3,UBE2I,SRC,PCNA,CFI,EIF4G1,CFL1 |
| GO:0072359 | circulatory system development | 10 | 872 | 0.61 | CCL2,FGF6,APOB,PIK3CA,MCAM,PCNA,EDN1,PGF,AKT1,VEGFA |
| GO:0031663 | lipopolysaccharide-mediated signaling pathway | 3 | 34 | 1.5 | CCL2,TNF,AKT1 |
| GO:2001233 | regulation of apoptotic signaling pathway | 7 | 409 | 0.78 | HGF,SOD1,MMP9,SRC,TNF,FIGNL1,AKT1 |
| GO:0032077 | positive regulation of deoxyribonuclease activity | 2 | 5 | 2.15 | PCNA,AKT1 |
| GO:0030155 | regulation of cell adhesion | 9 | 712 | 0.65 | CEACAM6,VCL,CCL2,PIK3CA,FLNA,SRC,TNF,AKT1,VEGFA |
| GO:0001938 | positive regulation of endothelial cell proliferation | 4 | 94 | 1.18 | CCL24,PGF,AKT1,VEGFA |
| GO:0048646 | anatomical structure formation involved in morphogenesis | 10 | 883 | 0.61 | CCL2,FGF6,PIK3CA,MCAM,MMP9,EDN1,CFL1,PGF,AKT1,VEGFA |
| GO:0051129 | negative regulation of cellular component organization | 9 | 713 | 0.65 | HGF,APP,FGF13,ARHGAP4,SRC,TNF,CRYAB,AKT1,VEGFA |
| GO:1904707 | positive regulation of vascular associated smooth muscle cell proliferation | 3 | 35 | 1.48 | MMP9,EDN1,TNF |
| GO:0045833 | negative regulation of lipid metabolic process | 4 | 95 | 1.18 | SOD1,DKK3,TNF,AKT1 |
| GO:0010942 | positive regulation of cell death | 9 | 719 | 0.65 | CCL2,CTSD,SOD1,APP,MMP9,SRC,TNF,EIF4G1,AKT1 |
| GO:0014065 | phosphatidylinositol 3-kinase signaling | 3 | 36 | 1.47 | PIK3CA,EDN1,AKT1 |
| GO:0016310 | phosphorylation | 12 | 1275 | 0.52 | NDUFB4,HGF,CCL2,FGF6,PIK3CA,APP,FGF13,SRC,TNF,CFL1,CRYAB,AKT1 |
| GO:0002690 | positive regulation of leukocyte chemotaxis | 4 | 98 | 1.16 | APP,EDN1,PGF,VEGFA |
| GO:0006801 | superoxide metabolic process | 3 | 37 | 1.46 | SOD1,EDN1,CCS |
| GO:0019216 | regulation of lipid metabolic process | 7 | 424 | 0.77 | APOB,SOD1,APP,SRC,DKK3,TNF,AKT1 |
| GO:0022407 | regulation of cell-cell adhesion | 7 | 424 | 0.77 | CEACAM6,CCL2,PIK3CA,SRC,TNF,AKT1,VEGFA |
| GO:0032870 | cellular response to hormone stimulus | 8 | 569 | 0.7 | APOB,SERPINF1,RPE65,PIK3CA,SRC,EDN1,PGF,AKT1 |
| GO:0071276 | cellular response to cadmium ion | 3 | 37 | 1.46 | SOD1,MMP9,AKT1 |
| GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 4 | 99 | 1.16 | MMP9,SRC,FIGNL1,AKT1 |
| GO:0031324 | negative regulation of cellular metabolic process | 18 | 2630 | 0.39 | HGF,C5,SERPINF1,PIK3CA,APP,PTX3,UBE2I,FLNA,MMP9,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0060754 | positive regulation of mast cell chemotaxis | 2 | 6 | 2.07 | PGF,VEGFA |
| GO:1903721 | positive regulation of I-kappaB phosphorylation | 2 | 6 | 2.07 | TNF,AKT1 |
| GO:0045765 | regulation of angiogenesis | 6 | 303 | 0.85 | HGF,SERPINF1,TNF,CCL24,PGF,VEGFA |
| GO:0002009 | morphogenesis of an epithelium | 7 | 435 | 0.76 | VCL,FLNA,SRC,EDN1,CFL1,PGF,VEGFA |
| GO:0008284 | positive regulation of cell population proliferation | 10 | 919 | 0.59 | CEACAM6,FGF6,FLNA,MMP9,EDN1,TNF,CCL24,PGF,AKT1,VEGFA |
| GO:0051050 | positive regulation of transport | 10 | 923 | 0.59 | CCL2,SOD1,APP,PTX3,FLNA,SRC,EDN1,TNF,AKT1,VEGFA |
| GO:0033043 | regulation of organelle organization | 12 | 1306 | 0.51 | HGF,APP,FGF13,FLNA,MMP9,SRC,EDN1,TNF,CCL24,CFL1,AKT1,VEGFA |
| GO:0035924 | cellular response to vascular endothelial growth factor stimulus | 3 | 40 | 1.43 | PGF,AKT1,VEGFA |
| GO:0042391 | regulation of membrane potential | 7 | 440 | 0.75 | SOD1,APP,FGF13,FLNA,SRC,EDN1,AKT1 |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 6 | 309 | 0.84 | FGF13,KIAA1598,FLNA,ARHGAP4,CFL1,VEGFA |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 5 | 196 | 0.96 | HGF,APP,SRC,TNF,VEGFA |
| GO:0044057 | regulation of system process | 8 | 592 | 0.68 | HGF,SOD1,APP,FGF13,FLNA,SRC,EDN1,AKT1 |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 17 | 2429 | 0.4 | HGF,C5,SERPINF1,APP,PTX3,UBE2I,FLNA,MMP9,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0071548 | response to dexamethasone | 3 | 41 | 1.42 | SERPINF1,PCNA,EDN1 |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 4 | 106 | 1.13 | HGF,SRC,TNF,AKT1 |
| GO:1902905 | positive regulation of supramolecular fiber organization | 5 | 198 | 0.95 | APP,FLNA,EDN1,CCL24,CFL1 |
| GO:0032496 | response to lipopolysaccharide | 6 | 313 | 0.83 | CCL2,APOB,SRC,EDN1,TNF,AKT1 |
| GO:0070555 | response to interleukin-1 | 5 | 199 | 0.95 | CCL2,APP,SRC,EDN1,CCL24 |
| GO:1901654 | response to ketone | 5 | 199 | 0.95 | SERPINF1,SRC,PCNA,EDN1,AKT1 |
| GO:0051054 | positive regulation of DNA metabolic process | 5 | 200 | 0.95 | HGF,SRC,PCNA,AKT1,VEGFA |
| GO:0009895 | negative regulation of catabolic process | 6 | 316 | 0.83 | HGF,PIK3CA,FLNA,TNF,EIF4G1,AKT1 |
| GO:0045123 | cellular extravasation | 3 | 42 | 1.41 | CCL2,SELPLG,TNF |
| GO:0060052 | neurofilament cytoskeleton organization | 2 | 7 | 2.01 | SOD1,NEFH |
| GO:0070527 | platelet aggregation | 3 | 42 | 1.41 | VCL,ITGA2B,FLNA |
| GO:0050778 | positive regulation of immune response | 8 | 607 | 0.67 | C5,CRP,PIK3CA,SRC,CFI,C1S,TNF,CFB |
| GO:0051345 | positive regulation of hydrolase activity | 9 | 772 | 0.62 | CCL2,CTSD,APP,ARHGAP4,PCNA,TNF,CCL24,AKT1,VEGFA |
| GO:0060326 | cell chemotaxis | 5 | 204 | 0.94 | HGF,C5,CCL2,CCL24,VEGFA |
| GO:0008406 | gonad development | 5 | 205 | 0.94 | SOD1,PTX3,FLNA,SRC,VEGFA |
| GO:0021782 | glial cell development | 4 | 112 | 1.1 | SOD1,APP,TNF,AKT1 |
| GO:0072593 | reactive oxygen species metabolic process | 4 | 112 | 1.1 | SOD1,EDN1,CCS,AKT1 |
| GO:0050877 | nervous system process | 12 | 1352 | 0.5 | CCL2,SERPINF1,RPE65,SOD1,APP,AZGP1,FGF13,EDN1,GUCA1A,TNF,AKT1,RBP3 |
| GO:0061387 | regulation of extent of cell growth | 4 | 113 | 1.1 | FGF13,KIAA1598,ARHGAP4,VEGFA |
| GO:0043200 | response to amino acid | 4 | 114 | 1.1 | PCNA,EDN1,TNF,CFL1 |
| GO:0006810 | transport | 24 | 4353 | 0.29 | CEACAM6,VCL,HGF,APOB,CTSD,CRP,VWF,ITGA2B,PIK3CA,SOD1,APP,AZGP1,PTX3,FGF13,CD5L,FLNA,MMP9,SRC,EDN1,CFI,CCS,AKT1,SLC25A16,VEGFA |
| GO:0032287 | peripheral nervous system myelin maintenance | 2 | 8 | 1.95 | SOD1,AKT1 |
| GO:0061042 | vascular wound healing | 2 | 8 | 1.95 | MCAM,VEGFA |
| GO:0002686 | negative regulation of leukocyte migration | 3 | 46 | 1.37 | C5,CCL2,AKT1 |
| GO:0010810 | regulation of cell-substrate adhesion | 5 | 212 | 0.92 | CEACAM6,VCL,FLNA,SRC,VEGFA |
| GO:0043523 | regulation of neuron apoptotic process | 5 | 212 | 0.92 | CCL2,PIK3CA,SOD1,APP,TNF |
| GO:0044087 | regulation of cellular component biogenesis | 10 | 971 | 0.56 | VCL,APP,FLNA,SRC,EDN1,TNF,CCL24,EIF4G1,CRYAB,VEGFA |
| GO:0044703 | multi-organism reproductive process | 10 | 971 | 0.56 | APOB,SOD1,APP,PTX3,MMP9,SRC,EDN1,FIGNL1,PGF,AKT1 |
| GO:1901653 | cellular response to peptide | 6 | 331 | 0.81 | RPE65,PIK3CA,APP,SRC,EDN1,AKT1 |
| GO:1905953 | negative regulation of lipid localization | 3 | 46 | 1.37 | CRP,TNF,AKT1 |
| GO:0044706 | multi-multicellular organism process | 5 | 213 | 0.92 | SOD1,MMP9,EDN1,PGF,AKT1 |
| GO:0051781 | positive regulation of cell division | 4 | 117 | 1.09 | FGF6,EDN1,PGF,VEGFA |
| GO:1901652 | response to peptide | 7 | 476 | 0.72 | RPE65,PIK3CA,APP,MMP9,SRC,EDN1,AKT1 |
| GO:0030198 | extracellular matrix organization | 6 | 338 | 0.8 | VWF,ITGA2B,APP,PTX3,MMP9,TNF |
| GO:0042542 | response to hydrogen peroxide | 4 | 119 | 1.08 | SOD1,SRC,PCNA,CRYAB |
| GO:0001952 | regulation of cell-matrix adhesion | 4 | 120 | 1.07 | CEACAM6,VCL,SRC,VEGFA |
| GO:0001666 | response to hypoxia | 6 | 342 | 0.8 | SRC,EDN1,CRYAB,PGF,AKT1,VEGFA |
| GO:0008228 | opsonization | 2 | 9 | 1.9 | CRP,PTX3 |
| GO:0060693 | regulation of branching involved in salivary gland morphogenesis | 2 | 9 | 1.9 | HGF,TNF |
| GO:0090199 | regulation of release of cytochrome c from mitochondria | 3 | 49 | 1.34 | HGF,MMP9,AKT1 |
| GO:1905906 | regulation of amyloid fibril formation | 2 | 9 | 1.9 | APP,CRYAB |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 3 | 50 | 1.33 | PIK3CA,SRC,AKT1 |
| GO:0010883 | regulation of lipid storage | 3 | 50 | 1.33 | APOB,CRP,TNF |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21 | 3600 | 0.32 | HGF,C5,CCL2,APOB,CTSD,CRP,PIK3CA,SOD1,APP,FGF13,UBE2I,MMP9,SRC,PCNA,EDN1,TNF,CCL24,EIF4G1,PGF,AKT1,VEGFA |
| GO:0048666 | neuron development | 9 | 827 | 0.59 | VCL,RPE65,PIK3CA,SOD1,APP,NEFH,KIAA1598,SRC,VEGFA |
| GO:0042063 | gliogenesis | 5 | 228 | 0.89 | CCL2,SOD1,APP,TNF,AKT1 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 5 | 228 | 0.89 | CCL2,PIK3CA,SRC,TNF,AKT1 |
| GO:1900122 | positive regulation of receptor binding | 2 | 10 | 1.85 | APP,MMP9 |
| GO:0043065 | positive regulation of apoptotic process | 8 | 660 | 0.63 | CCL2,CTSD,SOD1,APP,MMP9,SRC,TNF,AKT1 |
| GO:0098609 | cell-cell adhesion | 7 | 505 | 0.69 | CEACAM6,VCL,SELPLG,ITGA2B,FLNA,SRC,TNF |
| GO:0048754 | branching morphogenesis of an epithelial tube | 4 | 131 | 1.04 | SRC,EDN1,PGF,VEGFA |
| GO:1900180 | regulation of protein localization to nucleus | 4 | 131 | 1.04 | APP,FLNA,SRC,AKT1 |
| GO:0031295 | T cell costimulation | 3 | 55 | 1.29 | PIK3CA,SRC,AKT1 |
| GO:0032103 | positive regulation of response to external stimulus | 7 | 511 | 0.69 | APP,SRC,EDN1,TNF,CCL24,PGF,VEGFA |
| GO:0001878 | response to yeast | 2 | 11 | 1.81 | APP,PTX3 |
| GO:0009892 | negative regulation of metabolic process | 19 | 3124 | 0.34 | HGF,C5,SERPINF1,PIK3CA,SOD1,APP,PTX3,UBE2I,FLNA,MMP9,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0043276 | anoikis | 2 | 11 | 1.81 | PIK3CA,AKT1 |
| GO:0071803 | positive regulation of podosome assembly | 2 | 11 | 1.81 | SRC,TNF |
| GO:0000165 | MAPK cascade | 6 | 370 | 0.76 | HGF,CCL2,FGF6,FGF13,TNF,CRYAB |
| GO:0031175 | neuron projection development | 8 | 680 | 0.62 | VCL,PIK3CA,SOD1,APP,NEFH,KIAA1598,SRC,VEGFA |
| GO:0033993 | response to lipid | 9 | 858 | 0.57 | CCL2,APOB,SERPINF1,SRC,PCNA,EDN1,TNF,CRYAB,AKT1 |
| GO:0016043 | cellular component organization | 27 | 5447 | 0.25 | NDUFB4,VCL,CCL2,APOB,VWF,ITGA2B,PIK3CA,SOD1,APP,PTX3,NEFH,FGF13,KIAA1598,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,TNF,CCL24,FIGNL1,CFL1,CRYAB,AKT1,VEGFA |
| GO:0045666 | positive regulation of neuron differentiation | 6 | 377 | 0.75 | HGF,SERPINF1,APP,KIAA1598,EIF4G1,VEGFA |
| GO:0097746 | regulation of blood vessel diameter | 4 | 139 | 1.01 | CRP,SOD1,EDN1,AKT1 |
| GO:0002040 | sprouting angiogenesis | 3 | 59 | 1.26 | PGF,AKT1,VEGFA |
| GO:0071396 | cellular response to lipid | 7 | 528 | 0.67 | CCL2,APOB,SERPINF1,SRC,EDN1,TNF,AKT1 |
| GO:0031334 | positive regulation of protein-containing complex assembly | 5 | 249 | 0.85 | SRC,TNF,CCL24,EIF4G1,VEGFA |
| GO:0009620 | response to fungus | 3 | 61 | 1.24 | APP,PTX3,HTN3 |
| GO:0032722 | positive regulation of chemokine production | 3 | 61 | 1.24 | C5,APP,TNF |
| GO:0031644 | regulation of nervous system process | 4 | 144 | 0.99 | HGF,APP,SRC,EDN1 |
| GO:0000185 | activation of MAPKKK activity | 2 | 13 | 1.74 | APP,TNF |
| GO:0006957 | complement activation, alternative pathway | 2 | 13 | 1.74 | C5,CFB |
| GO:0007266 | Rho protein signal transduction | 3 | 62 | 1.24 | KIAA1598,ARHGAP4,CFL1 |
| GO:0010823 | negative regulation of mitochondrion organization | 3 | 62 | 1.24 | HGF,APP,AKT1 |
| GO:0019430 | removal of superoxide radicals | 2 | 13 | 1.74 | SOD1,CCS |
| GO:0044793 | negative regulation by host of viral process | 2 | 13 | 1.74 | CRP,PTX3 |
| GO:0045787 | positive regulation of cell cycle | 6 | 388 | 0.74 | APP,SRC,PCNA,EDN1,EIF4G1,AKT1 |
| GO:1902931 | negative regulation of alcohol biosynthetic process | 2 | 13 | 1.74 | SOD1,DKK3 |
| GO:1902947 | regulation of tau-protein kinase activity | 2 | 13 | 1.74 | HGF,APP |
| GO:0044089 | positive regulation of cellular component biogenesis | 7 | 542 | 0.66 | FLNA,SRC,EDN1,TNF,CCL24,EIF4G1,VEGFA |
| GO:0051384 | response to glucocorticoid | 4 | 147 | 0.99 | SERPINF1,PCNA,EDN1,TNF |
| GO:0051893 | regulation of focal adhesion assembly | 3 | 63 | 1.23 | VCL,SRC,VEGFA |
| GO:0050776 | regulation of immune response | 9 | 896 | 0.55 | C5,CRP,PIK3CA,CD5L,SRC,CFI,C1S,TNF,CFB |
| GO:0060627 | regulation of vesicle-mediated transport | 7 | 550 | 0.66 | CCL2,SOD1,APP,PTX3,SRC,TNF,VEGFA |
| GO:0098962 | regulation of postsynaptic neurotransmitter receptor activity | 2 | 14 | 1.71 | APP,SRC |
| GO:2000401 | regulation of lymphocyte migration | 3 | 65 | 1.22 | CCL2,APP,AKT1 |
| GO:1901564 | organonitrogen compound metabolic process | 26 | 5244 | 0.25 | HGF,CCL2,FGF6,APOB,CTSD,VWF,PIK3CA,SOD1,APP,FGF13,UBE2I,CD5L,FLNA,MMP9,SRC,PCNA,CFI,C1S,TNF,EIF4G1,CFB,CFL1,CRYAB,CCS,AKT1,RBP3 |
| GO:0030856 | regulation of epithelial cell differentiation | 4 | 151 | 0.97 | VCL,MMP9,TNF,VEGFA |
| GO:0007017 | microtubule-based process | 8 | 727 | 0.59 | APOB,SOD1,APP,NEFH,FGF13,FLNA,FIGNL1,CRYAB |
| GO:0045834 | positive regulation of lipid metabolic process | 4 | 152 | 0.97 | APP,SRC,TNF,AKT1 |
| GO:0060429 | epithelium development | 10 | 1109 | 0.51 | VCL,SOD1,FLNA,SRC,PCNA,EDN1,CFL1,PGF,AKT1,VEGFA |
| GO:0034762 | regulation of transmembrane transport | 7 | 560 | 0.65 | CCL2,APP,FLNA,MMP9,EDN1,TNF,AKT1 |
| GO:0043542 | endothelial cell migration | 3 | 67 | 1.2 | PIK3CA,AKT1,VEGFA |
| GO:0071375 | cellular response to peptide hormone stimulus | 5 | 269 | 0.82 | RPE65,PIK3CA,SRC,EDN1,AKT1 |
| GO:0042159 | lipoprotein catabolic process | 2 | 15 | 1.68 | APOB,CTSD |
| GO:0050930 | induction of positive chemotaxis | 2 | 15 | 1.68 | PGF,VEGFA |
| GO:2000402 | negative regulation of lymphocyte migration | 2 | 15 | 1.68 | CCL2,AKT1 |
| GO:0048511 | rhythmic process | 5 | 271 | 0.82 | SERPINF1,RPE65,PTX3,SRC,PCNA |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 5 | 271 | 0.82 | APP,EDN1,TNF,AKT1,VEGFA |
| GO:0045931 | positive regulation of mitotic cell cycle | 4 | 156 | 0.96 | APP,EDN1,EIF4G1,AKT1 |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 4 | 156 | 0.96 | CCL2,PCNA,EIF4G1,AKT1 |
| GO:0040014 | regulation of multicellular organism growth | 3 | 69 | 1.19 | PIK3CA,SOD1,APP |
| GO:0051049 | regulation of transport | 13 | 1776 | 0.42 | CCL2,SOD1,APP,PTX3,NEFH,FLNA,MMP9,SRC,EDN1,TNF,CRYAB,AKT1,VEGFA |
| GO:0045321 | leukocyte activation | 9 | 929 | 0.54 | CEACAM6,VCL,SELPLG,CTSD,APP,PTX3,MMP9,EDN1,TNF |
| GO:0010629 | negative regulation of gene expression | 14 | 2014 | 0.39 | HGF,SERPINF1,APP,UBE2I,FLNA,SRC,PCNA,EDN1,DKK3,TNF,EIF4G1,CRYAB,AKT1,VEGFA |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion | 2 | 16 | 1.65 | CEACAM6,TNF |
| GO:0042554 | superoxide anion generation | 2 | 16 | 1.65 | SOD1,EDN1 |
| GO:0051044 | positive regulation of membrane protein ectodomain proteolysis | 2 | 16 | 1.65 | APP,TNF |
| GO:2001224 | positive regulation of neuron migration | 2 | 16 | 1.65 | KIAA1598,FLNA |
| GO:0002697 | regulation of immune effector process | 6 | 418 | 0.71 | C5,CD5L,CFI,C1S,TNF,CFB |
| GO:1902117 | positive regulation of organelle assembly | 3 | 71 | 1.18 | SRC,EDN1,TNF |
| GO:0048608 | reproductive structure development | 6 | 420 | 0.71 | SOD1,PTX3,FLNA,SRC,AKT1,VEGFA |
| GO:0006937 | regulation of muscle contraction | 4 | 162 | 0.94 | SOD1,FGF13,FLNA,EDN1 |
| GO:0034329 | cell junction assembly | 5 | 280 | 0.8 | VCL,APP,FGF13,FLNA,SRC |
| GO:0032874 | positive regulation of stress-activated MAPK cascade | 4 | 164 | 0.94 | APP,EDN1,TNF,VEGFA |
| GO:0002274 | myeloid leukocyte activation | 7 | 585 | 0.63 | CEACAM6,VCL,CTSD,APP,PTX3,MMP9,TNF |
| GO:1900221 | regulation of amyloid-beta clearance | 2 | 17 | 1.62 | APP,TNF |
| GO:1903209 | positive regulation of oxidative stress-induced cell death | 2 | 17 | 1.62 | SOD1,APP |
| GO:2000010 | positive regulation of protein localization to cell surface | 2 | 17 | 1.62 | TNF,AKT1 |
| GO:0010827 | regulation of glucose transmembrane transport | 3 | 74 | 1.16 | EDN1,TNF,AKT1 |
| GO:0050794 | regulation of cellular process | 42 | 10932 | 0.14 | CEACAM6,VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,SERPINF1,CRP,RPE65,ITGA2B,PIK3CA,MCAM,SOD1,APP,WIF1,AZGP1,PTX3,NEFH,FGF13,KIAA1598,UBE2I,CD5L,FLNA,ARHGAP4,FRAT2,MMP9,SRC,PCNA,EDN1,GUCA1A,DKK3,TNF,CCL24,FIGNL1,EIF4G1,CFL1,CRYAB,PGF,AKT1,VEGFA |
| GO:0009314 | response to radiation | 6 | 431 | 0.69 | RPE65,APP,PCNA,FIGNL1,CRYAB,AKT1 |
| GO:0007422 | peripheral nervous system development | 3 | 75 | 1.15 | SOD1,NEFH,AKT1 |
| GO:0031100 | animal organ regeneration | 3 | 75 | 1.15 | HGF,PCNA,PGF |
| GO:0051881 | regulation of mitochondrial membrane potential | 3 | 75 | 1.15 | SOD1,SRC,AKT1 |
| GO:0032869 | cellular response to insulin stimulus | 4 | 169 | 0.93 | RPE65,PIK3CA,SRC,AKT1 |
| GO:0045766 | positive regulation of angiogenesis | 4 | 169 | 0.93 | HGF,CCL24,PGF,VEGFA |
| GO:1903522 | regulation of blood circulation | 5 | 292 | 0.78 | APP,FGF13,FLNA,EDN1,AKT1 |
| GO:0009887 | animal organ morphogenesis | 9 | 967 | 0.52 | CCL2,FGF6,RPE65,SOD1,SRC,EDN1,TNF,PGF,VEGFA |
| GO:0051090 | regulation of DNA-binding transcription factor activity | 6 | 437 | 0.69 | APP,FLNA,EDN1,TNF,AKT1,VEGFA |
| GO:0009615 | response to virus | 5 | 293 | 0.78 | APOB,FLNA,SRC,TNF,CFL1 |
| GO:0030030 | cell projection organization | 10 | 1170 | 0.48 | VCL,PIK3CA,SOD1,APP,NEFH,KIAA1598,FLNA,SRC,AKT1,VEGFA |
| GO:0090068 | positive regulation of cell cycle process | 5 | 294 | 0.78 | APP,PCNA,EDN1,EIF4G1,AKT1 |
| GO:0001667 | ameboidal-type cell migration | 4 | 173 | 0.92 | PIK3CA,CFL1,AKT1,VEGFA |
| GO:0099601 | regulation of neurotransmitter receptor activity | 3 | 78 | 1.14 | CCL2,APP,SRC |
| GO:0003012 | muscle system process | 5 | 297 | 0.78 | VCL,PIK3CA,SOD1,EDN1,CRYAB |
| GO:0002689 | negative regulation of leukocyte chemotaxis | 2 | 19 | 1.57 | C5,CCL2 |
| GO:0048245 | eosinophil chemotaxis | 2 | 19 | 1.57 | CCL2,CCL24 |
| GO:0050901 | leukocyte tethering or rolling | 2 | 19 | 1.57 | SELPLG,TNF |
| HSA-168256 | Immune System | 25 | 1956 | 0.66 | CEACAM6,VCL,HGF,C5,CCL2,APOB,CTSD,CRP,PIK3CA,SOD1,APP,PTX3,S100A7A,FLNA,MMP9,SRC,CFI,C1S,TNF,EIF4G1,CFB,HTN3,CFL1,AKT1,VEGFA |
| HSA-76002 | Platelet activation, signaling and aggregation | 12 | 260 | 1.22 | VCL,HGF,VWF,ITGA2B,PIK3CA,SOD1,APP,FLNA,SRC,CFL1,AKT1,VEGFA |
| HSA-109582 | Hemostasis | 15 | 605 | 0.95 | CEACAM6,VCL,HGF,SELPLG,APOB,VWF,ITGA2B,PIK3CA,SOD1,APP,FLNA,SRC,CFL1,AKT1,VEGFA |
| HSA-114608 | Platelet degranulation | 9 | 127 | 1.4 | VCL,HGF,VWF,ITGA2B,SOD1,APP,FLNA,CFL1,VEGFA |
| HSA-162582 | Signal Transduction | 27 | 2741 | 0.54 | VCL,HGF,C5,CCL2,FGF6,APOB,CTSD,VWF,RPE65,ITGA2B,PIK3CA,APP,WIF1,FLNA,ARHGAP4,FRAT2,MMP9,SRC,EDN1,GUCA1A,TNF,EIF4G1,CFL1,PGF,AKT1,RBP3,VEGFA |
| HSA-168249 | Innate Immune System | 17 | 1025 | 0.77 | CEACAM6,VCL,C5,APOB,CTSD,CRP,PIK3CA,APP,PTX3,S100A7A,MMP9,SRC,CFI,C1S,CFB,HTN3,CFL1 |
| HSA-1280215 | Cytokine Signaling in Immune system | 12 | 681 | 0.8 | HGF,CCL2,PIK3CA,SOD1,APP,FLNA,MMP9,TNF,EIF4G1,CFL1,AKT1,VEGFA |
| HSA-449147 | Signaling by Interleukins | 10 | 440 | 0.91 | HGF,CCL2,PIK3CA,SOD1,APP,MMP9,TNF,CFL1,AKT1,VEGFA |
| HSA-166658 | Complement cascade | 5 | 57 | 1.49 | C5,CRP,CFI,C1S,CFB |
| HSA-6785807 | Interleukin-4 and Interleukin-13 signaling | 6 | 107 | 1.3 | HGF,CCL2,MMP9,TNF,AKT1,VEGFA |
| HSA-354192 | Integrin signaling | 4 | 27 | 1.72 | VWF,ITGA2B,SRC,AKT1 |
| HSA-6802948 | Signaling by high-kinase activity BRAF mutants | 4 | 36 | 1.6 | VCL,VWF,ITGA2B,SRC |
| HSA-5674135 | MAP2K and MAPK activation | 4 | 40 | 1.55 | VCL,VWF,ITGA2B,SRC |
| HSA-9656223 | Signaling by RAF1 mutants | 4 | 41 | 1.54 | VCL,VWF,ITGA2B,SRC |
| HSA-430116 | GP1b-IX-V activation signalling | 3 | 12 | 1.95 | VWF,FLNA,SRC |
| HSA-194138 | Signaling by VEGF | 5 | 106 | 1.22 | PIK3CA,SRC,PGF,AKT1,VEGFA |
| HSA-2219528 | PI3K/AKT Signaling in Cancer | 5 | 105 | 1.23 | HGF,FGF6,PIK3CA,SRC,AKT1 |
| HSA-354194 | GRB2:SOS provides linkage to MAPK signaling for Integrins | 3 | 15 | 1.85 | VWF,ITGA2B,SRC |
| HSA-372708 | p130Cas linkage to MAPK signaling for integrins | 3 | 15 | 1.85 | VWF,ITGA2B,SRC |
| HSA-5663202 | Diseases of signal transduction by growth factor receptors and second messengers | 8 | 392 | 0.86 | VCL,HGF,FGF6,VWF,ITGA2B,PIK3CA,SRC,AKT1 |
| HSA-5673001 | RAF/MAP kinase cascade | 7 | 274 | 0.96 | VCL,HGF,FGF6,VWF,ITGA2B,PIK3CA,SRC |
| HSA-6802946 | Signaling by moderate kinase activity BRAF mutants | 4 | 45 | 1.5 | VCL,VWF,ITGA2B,SRC |
| HSA-6802955 | Paradoxical activation of RAF signaling by kinase inactive BRAF | 4 | 45 | 1.5 | VCL,VWF,ITGA2B,SRC |
| HSA-6811558 | PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | 5 | 105 | 1.23 | HGF,FGF6,PIK3CA,SRC,AKT1 |
| HSA-9649948 | Signaling downstream of RAS mutants | 4 | 45 | 1.5 | VCL,VWF,ITGA2B,SRC |
| HSA-977606 | Regulation of Complement cascade | 4 | 47 | 1.48 | C5,CFI,C1S,CFB |
| HSA-6802952 | Signaling by BRAF and RAF fusions | 4 | 65 | 1.34 | VCL,VWF,ITGA2B,SRC |
| HSA-166663 | Initial triggering of complement | 3 | 22 | 1.69 | CRP,C1S,CFB |
| HSA-202733 | Cell surface interactions at the vascular wall | 5 | 138 | 1.11 | CEACAM6,SELPLG,APOB,PIK3CA,SRC |
| HSA-9009391 | Extra-nuclear estrogen signaling | 4 | 74 | 1.28 | PIK3CA,MMP9,SRC,AKT1 |
| HSA-2219530 | Constitutive Signaling by Aberrant PI3K in Cancer | 4 | 78 | 1.26 | HGF,FGF6,PIK3CA,SRC |
| HSA-9006934 | Signaling by Receptor Tyrosine Kinases | 8 | 502 | 0.75 | HGF,FGF6,PIK3CA,MMP9,SRC,PGF,AKT1,VEGFA |