159 Biomarkers
| Biomarker | Source | Application | Reference |
|---|---|---|---|
| VIPR2 | chromosome | prediction | Yiu WC,et al.PLoS One. 2013 |
| vasoactive intestinal peptide receptor 2 (VIPR2) | chromosome | prediction | Yiu WC,et al.PLoS One. 2013 |
| FXIII-A 185-T-Allele | chromosome | prognosis | Parmeggiani F,et al. Int J Mol Sci. 2015 |
| FXIII-A 185-T-Allele | chromosome | prognosis | Parmeggiani F,et al. Int J Mol Sci. 2015 |
| rs10033900 | chromosome | prediction | Leveziel N,et al.Invest Ophthalmol Vis Sci. 2012 |
| rs769455 in the APOE gene | chromosome | prediction | Leveziel N,et al.Invest Ophthalmol Vis Sci. 2012 |
| NDUFAF7 | chromosome | prediction | Wang B,et al. Invest Ophthalmol Vis Sci. 2017 |
| mitofusin 1(MFN1) | chromosome | prediction | Andrew T,PLoS Genet. 2008 |
| presenilin associated rhomboid like (PSARL) | chromosome | prediction | Andrew T,PLoS Genet. 2008 |
| SOX2 overlapping transcript(SOX2OT) | chromosome | prediction | Andrew T,PLoS Genet. 2008 |
| uromodulin Like 1 (UMODL1) | chromosome | prediction | Zhu MM,BMC Med Genet. 2012. |
| uromodulin Like 1 (UMODL1) | chromosome | prediction | Zhu MM,BMC Med Genet. 2012. |
| ACE | blood | prediction | Syed Tasleem Raza et al. Oman J Ophthalmol , 2017 |
| CYP46A1 | blood | prediction | Syed Tasleem Raza et al. Oman J Ophthalmol , 2017 |
| CYP46A1 | blood | prediction | Syed Tasleem Raza et al. Oman J Ophthalmol , 2017 |
| CYP46A1 | blood | prediction | Syed Tasleem Raza et al. Oman J Ophthalmol , 2017 |
| CYP46A1 | Blood samples | prediction | Anu Chandra et al，Middle East Afr J Ophthalmol. 2016 Apr-Jun |
| PPARγ2 | Blood samples | prediction | Anu Chandra et al，Middle East Afr J Ophthalmol. 2016 Apr-Jun |
| CACNA1A | blood | prediction | Tin Aung et al.Nat Genet . 2015 |
| LOXL1 | blood | prediction | Tin Aung et al.Nat Genet . 2015 |
| TDRD7 | plasma | prediction | Seong Taeck Kim et al,Korean J Ophthalmol . 2014 |
| CRYBB1 | blood | diagnosis | Cohen, David et al. Investigative ophthalmology & visual science vol. 2008 |
| paraoxonase 1 (PON1) | blood | diagnosis | Hashim, Zehra, and Shamshad Zarina. Clinical biochemistry vol. 2007 |
| CRYBA4 | Tissue | diagnosis | Billingsley, Gail et al. American journal of human genetics vol. 2006 |
| HSF4 | blood | diagnosis | Ke, Tie et al. American journal of ophthalmology vol. 2006 |
| CRYBB2 | diagnosis | Yao, Ke et al. Molecular vision vol. 2005 | |
| crystallin gamma S (CRYGS) | blood | diagnosis | Sun, H et al. Journal of medical genetics vol. 2005 |
| LIPC | blood | prediction | Reynolds, Robyn et al. Ophthalmology vol. 2010 |
| KCTD10 | blood | diagnosis | Rasa Liutkeviciene et al.Dis Markers . 2019 |
| ERCC6 | blood | diagnosis | Rasa Liutkeviciene et al.Dis Markers . 2019 |
| HTRA1 | blood | diagnosis | Rasa Liutkeviciene et al.Dis Markers . 2019 |
| rs3793784 | blood | diagnosis | Rasa Liutkeviciene et al.Dis Markers . 2020 |
| rs56209061 | blood | diagnosis | Rasa Liutkeviciene et al.Dis Markers . 2020 |
| Mn-SOD | blood | diagnosis | Khaled K Abu-Amero et al.Ophthalmic Genet . 2014 |
| RAGE | Venous blood specimens | diagnosis | H.M. Zhang J. Endocrinol. Invest, 2009 |
| GALC | blood | diagnosis | Yutao Liu et al.PLoS One . 2011 |
| CYP46A1 | diagnosis | Cynthia Fourgeux et al.Invest Ophthalmol Vis Sci . 2009 | |
| TDRD7 | plasma | prediction | Seong Taeck Kim et al,Korean J Ophthalmol . 2014 |
| FABP2 | blood samples | prediction | Shania Abbas et al,Meta Gene . 2014 |
| PPARG2 | blood samples | prediction | Shania Abbas et al,Meta Gene . 2014 |
| TRPC6 | leukocytes of the peripheral blood | prediction | Shida Chen et al,Clin Exp Ophthalmol . 2013 |
| SPAG16 | prediction | Shipra Mehra,et al,J Biomark . 2013 | |
| complement factor H gene | blood | prognosis | Imai, Daisuke et al. Journal of ocular biology, diseases, and informatics vol. 2010 |
| high-temperature requirement A-1 (HTRA1) | blood | prognosis | Imai, Daisuke et al. Journal of ocular biology, diseases, and informatics vol. 2010 |
| vascular endothelial growth factor gene | blood | prognosis | Imai, Daisuke et al. Journal of ocular biology, diseases, and informatics vol. 2010 |
| CFH | blood | diagnosis | Marioli, Dimitra I et al. Graefe's archive for clinical and experimental ophthalmology vol. 2009 |
| ARMS2 | blood | diagnosis | Gu, Jiayin et al. Molecular & cellular proteomics : MCP vol.2009 |
| HTRA1 | blood | diagnosis | Gu, Jiayin et al. Molecular & cellular proteomics : MCP vol.2009 |
| VEGF | diagnosis | Szaflik, Jacek P et al. Klinika oczna vol. 2009 | |
| CFH | blood | diagnosis | Seddon, Johanna M et al. Investigative ophthalmology & visual science vol.2009 |
| CFH | blood | diagnosis | Seddon, Johanna M et al. Investigative ophthalmology & visual science vol.2009 |
| IGF1 | DNA | prediction | Mak JY et al.Arch Ophthalmol. 2012 |
| HGF | DNA | prediction | Yanovitch T et al.Mol Vis. 2009 |
| HGF | DNA | prediction | Yanovitch T et al.Mol Vis. 2009 |
| HGF | DNA | prediction | Yanovitch T et al.Mol Vis. 2009 |
| MYP1 | chromosome | prediction | Ratnamala U,et al. Invest Ophthalmol Vis Sci. 2011 |
| PAX6 | chromosome | prediction | Tsai YY, et al.Eye (Lond). 2008 |
| PDGFRA | chromosome | prediction | Yuan XL,et al.Ophthalmic Genet. 2021 |
| MTOR | chromosome | prediction | Yuan XL,et al.Ophthalmic Genet. 2021 |
| WNT7B | chromosome | prediction | Yuan XL,et al.Ophthalmic Genet. 2021 |
| CMPK1 | chromosome | prediction | Yuan XL,et al.Ophthalmic Genet. 2021 |
| RBP3 | chromosome | prediction | Yuan XL,et al.Ophthalmic Genet. 2021 |
| MYP2 | tissue | prediction | Farbrother JE,Invest Ophthalmol Vis Sci. 2004 |
| 12q (MYP3) | tissue | prediction | Farbrother JE,Invest Ophthalmol Vis Sci. 2004 |
| 17q | tissue | prediction | Farbrother JE,Invest Ophthalmol Vis Sci. 2004 |
| NLRP3 | tissue | diagnosis | Hui Chen，Invest Ophthalmol Vis Sci . 2020 |
| TGFB1 | tissue | diagnosis | Hui Chen，Invest Ophthalmol Vis Sci . 2020 |
| CCL2 | tissue | diagnosis | Hui Chen，Invest Ophthalmol Vis Sci . 2020 |
| angiotensin-converting enzyme (ACE) | serum samples | prediction | I Degirmenci，Int J Clin Prac,2005 |
| EPHA2 | whole blood or saliva or buccal swab | prediction | Alpana Dave et al,PLoS One . 2013 |
| FTL | blood leukocytes | prediction | Thomas M Bennett et al,Mol Vis . 2013 |
| D2S439 | plasma | prediction | Shipra Mehra et al,Free Radic Res . 2012 Feb |
| αA-crystallin gene (CRYAA) | peripheral blood leukocytes | prediction | Binbin Wang et al,Ophthalmic Genet . 2012 Sep |
| GJA3 | blood lymphocytes leukocytes | prediction | Lu Zhang et al,Mol Vis . 2012 |
| CFH | blood | prediction | Kaur, Inderjeet et al. Investigative ophthalmology & visual science vol. 2006 |
| TLR4 | blood | prediction | Kaur, Inderjeet et al. Investigative ophthalmology & visual science vol. 2006 |
| APOE | blood | prediction | Kaur, Inderjeet et al. Investigative ophthalmology & visual science vol. 2006 |
| GSTM1 | blood | prediction | Oz, O et al. European journal of ophthalmology vol. 2003 |
| GSTP1 | blood | prediction | Oz, O et al. European journal of ophthalmology vol. 2003 |
| GSTT1 | blood | prediction | Oz, O et al. European journal of ophthalmology vol. 2003 |
| mitochondrial DNA mutation | machine | diagnosis | Michaelides, Michel et al.Archives of ophthalmology (Chicago, Ill. : 1960) vol. 2008 |
| A3244G mitochondrial DNA | machine | diagnosis | Michaelides, Michel et al.Archives of ophthalmology (Chicago, Ill. : 1960) vol. 2008 |
| transient receptor potential cation channel 6 | DNA | diagnosis | Chen S, Clin Exp Ophthalmol. 2013 |
| insulin-like growth factor-II | chromosome | diagnosis | Tsai FJ,J Clin Lab Anal. 2003 |
| superoxide dismutase (SOD2) | chromosome | prediction | Abu-Amero, Khaled K et al. Ophthalmic genetics vol. 36,2 (2015) |
| tumour necrosis factor alpha | chromosome | diagnosis | Lin HJ,Eye (Lond). 2003 |
| SIX6 | blood | diagnosis/prediction | Shi Song Rong et al.Exp Eye Res . 2019 |
| RAGE | Blood | prognosis | Mantas Banevicius et al,Med Sci Monit . 2018 |
| complement factor H (CFH) | treatment | Nan Hong et al,Acta Ophthalmol . 2016 | |
| VEGF haplotype TGA | treatment/prognosis | I Habibi et al,Klin Monbl Augenheilkd . 2016 | |
| OPA1 | blood | prediction | Mabuchi, Fumihiko et al. American journal of ophthalmology vol. 2007 |
| myocilin | blood | diagnosis | Baird, Paul N et al. Human genetics vol. 2005 |
| IL-1 | blood | prediction | Lin, Hui-Ju et al. Zeitschrift fur Augenheilkunde vol. 2003 |
| myocilin | blood | progression | Polansky, J R et al. Clinical genetics vol. 200. |
| IGF-II | blood | prediction | Tsai, Fuu-Jen et al. Journal of clinical laboratory analysis vol. 200. |
| tumour necrosis factor alpha -308 gene | blood | prediction | Lin, H-J et al. Eye (London, England) vol.2003 |
| 10p12.31 | Tissue | diagnosis | Kim K et al.Eur J Hum Genet. 2014 |
| NCK2 | DNA | prediction | Akiyama M et al.Br J Ophthalmol. 2008 |
| manganese superoxide dismutase gene (Mn-SOD) | DNA | prediction | Abu-Amero KK et al.Ophthalmic Genet. 2014 |
| LOXL1 | Tissue | prediction | Fan BJ et al.BMC Med Genet. 2008 |
| CYP1B1 | chromosome | prediction | Belmouden A,Clin Genet. 2002 |
| p53 | chromosome | prediction | Acharya M,Mol Vis. 2002 |
| OPA1 | chromosome | diagnosis | Aung T,Hum Genet. 2002 |
| 2p16 | chromosome | prediction | Jiao X, Epub 2009 |
| SNPs on chromosome 2p | chromosome | prediction | Balasubbu S,Invest Ophthalmol Vis Sci. 2012 |
| SNPs on chromosome 2p | chromosome | prediction | Balasubbu S,Invest Ophthalmol Vis Sci. 2012 |
| ENPP1 variants | machine | prognosis | Gohari-Lasaki, Sahar et al. International ophthalmology vol. 2020 |
| VDR | Xing Zhong et al. Gene. 2015 | ||
| VEGF | tissue | progression | Min-Young Chun，J Clin Endocrinol Metab . 2010 |
| eNOS | tissue | diagnosis | Intissar Ezzidi，Clin Endocrinol (Oxf) . 2008 |
| a combinatorial molecular signature | serum samples | diagnosis | Jianbo Pan，Mol Vis . 2016 |
| NRXN1 | meta-analyses | prediction | Qing Li et al.Hum Genet . 2015 |
| TOX | meta-analyses | prediction | Qing Li et al.Hum Genet . 2015 |
| LINC00340 | meta-analyses | prediction | Qing Li et al.Hum Genet . 2015 |
| OPA1 | blood | prediction | Fumihiko Mabuchi et al.Am J Ophthalmol . 2007 |
| nanophthalmos (NNO1) | tissue | diagnosis | M I Othman et.alAm J Hum Genet . 1998 |
| CYP46A1 | blood | prediction | Anu Chandra Middle East Afr J Ophthalmol . Apr-Jun 2016 |
| PPARγ2 | blood | prediction | Anu Chandra Middle East Afr J Ophthalmol . Apr-Jun 2016 |
| IL-1beta | blood | prediction | Hui-Ju Lin full text links full text provider logo actions Cite Favorites share page navigation Title & authors Abstract Similar articles Cited by MeSH terms Substances Related information LinkOut - more resources Ophthalmologica . Sep-Oct 2003 |
| MLIP | blood | prediction | María I Canut Sci Rep . 2021 |
| MYOC | analysis | diagnosis | Owen M Siggs JAMA Ophthalmol . 2021 |
| the unfolded protein response (UPR) | blood | prognosis | Aparna Rao Clin Ophthalmol . 2020 |
| ACE | diagnosis | Abdolrahim Nikzamir et al. Ophthalmic Genet. 2010 | |
| vascular endothelial growth factor -634C/G polymorphism | plasma | prediction | Ying Yang et al. Exp Biol Med (Maywood). 2010 |
| VEGF | sample | prediction | Asmaa Kamal，Int J Ophthalmol . 2016 |
| SOD1 | Leila Saremi et al.J Diabetes Metab Disord.2021 | ||
| EFEMP1 | diagnosis | Lu Cheng et al.Front Pharmacol . 2021 | |
| alpha A-crystallin (CRYAA ) | peripheral blood | prediction | Zhennan Zhao et al.BMC Ophthalmol . 2017 |
| rs13053109 | peripheral blood | prediction | Zhennan Zhao et al.BMC Ophthalmol . 2017 |
| rs7278468 | peripheral blood | prediction | Zhennan Zhao et al.BMC Ophthalmol . 2017 |
| age-related maculopathy susceptibility 2 (ARMS2) | peripheral blood | prediction | Nichole Joachim et al.Ophthalmology . 2015 |
| factor XIII-A gene (FXIII-A-G185T) | treatment | Francesco Parmeggiani et al.Int J Mol Sci . 2015 | |
| ARMS2 | machine | prediction | L Huang et al.Eye (Lond) . 2015 |
| ARMS2/HTRA1 | machine | prediction | L Huang et al.Eye (Lond) . 2015 |
| CFH | machine | prediction | L Huang et al.Eye (Lond) . 2015 |
| CFH | machine | prediction | L Huang et al.Eye (Lond) . 2015 |
| ARMS2 | machine | prediction | Zizhong Hu et al.Br J Ophthalmol . 2015 |
| C3 | prediction | Ioannis Havvas et al.Eur J Ophthalmol .2014 | |
| rs641153 | prediction | Ioannis Havvas et al.Eur J Ophthalmol .2014 | |
| rs12614 | prediction | Ioannis Havvas et al.Eur J Ophthalmol .2014 | |
| C3 G allele | prediction | Ioannis Havvas et al.Eur J Ophthalmol .2014 | |
| complement factor H gene | plasma | prediction | Zhao-Yang Wang et al.PLoS One . 2014 |
| SCA7 | plasma | prediction | J J Magaña et al.Cerebellum . 2013 |
| ARMS2 | plasma | prediction | Yeong Hoon Kim et al.Ophthalmic Genet . 2013 |
| IL-8 | whole blood | prediction | Federico Ricci et al.PLoS One . 2013 |
| ARMS2 | machine | prediction | Stephen G Schwartz et al.Retina . 2012 |
| CFH | plasma | prediction | Dzenita Smailhodzic et al.Ophthalmology . 2012 |
| ARMS2 | plasma | prediction | Dzenita Smailhodzic et al.Ophthalmology . 2012 |
| complement factor H (CFH) | blood | prediction | Milam A Brantley Jr et al.Am J Ophthalmol . 2012 |
| IGFR1R | venous blood | prediction | M Yu Kirilenko et al.Vestn Oftalmol . 2017 |
| combination of the C VEGF-A and T IGFR-1 genetic variants | venous blood | prediction | M Yu Kirilenko et al.Vestn Oftalmol . 2017 |
| combination of the C VEGF-A and T IGFR-1 genetic variants | venous blood | prediction | M Yu Kirilenko et al.Vestn Oftalmol . 2017 |
| MTHFR | blood | prediction | Hamoud Al-Shahrani et al.BMC Ophthalmol . 2016 |
| CYP46A1 | blood | prediction | Anu Chandra et al.Middle East Afr J Ophthalmol . 2016 |
| PPARγ2 | blood | prediction | Anu Chandra et al.Middle East Afr J Ophthalmol . 2016 |
| ACVR1 | tissue | prediction | Altaf A Kondkar J Investig Med . 2021 |
| Loss of heterozygosity (LOH) | tissue | prediction | V P Kozobolis .Invest Ophthalmol Vis Sci . 1999 |
| CYP46A1 | blood | prediction | Syed Tasleem Raza .Oman J Ophthalmol . Jan-Apr 2017 |
| CFH | blood | prediction | Ming Ming Yang .Front Immunol . 2021 |