Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Gut Microbiota
Category	Molecular Changes
Affected targets	Adipose Tissue Aging
Hallmarks	Altered Intercellular Communication
Molecular	RNA
Description	At the gastrointestinal level, aging entails the impairment of intestinal motility and increased permeability, as well as changes to the intestinal nervous system and associated alterations in GM
EXPERIMENT INFORMATION
Region	Italy
Race	white
Samples	92
Age	/
Gender	/
Application	Predictive
Conclusion	Overall, the main biomarkers associated with centenarians belonged to the verrucomicrobia phylum, including the akkermansia muciniphila species, considered to be a significant biomarker of gut homeostasis for its ability to promote intestinal integrity; at the same time, there is a significant increase in taxa with an anti-inflammatory phenotype, biomarkers of a state of health. this intestinal microbial ecosystem could guarantee intestinal health, which would then translate into the health of the whole organism.
Reference	Aldo Manzin, Nutrients, 2022
Details	PMID:35745166 (Click to Pubmed) ； IF: ； Citation:
Confidence