Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Telomere Length
Category	Molecular Changes
Affected targets	Immune System Aging
Hallmarks	Telomere Attrition
Molecular	DNA
Description	Telomeres, the protective caps on the ends of chromosomes, play a key role in chromosomal stability.? When telomeres become critically short, cells enter a state of replicative arrest
EXPERIMENT INFORMATION
Region	worldwide
Race	multiple racial
Samples	208(events occur)/205(control group)
Age	59.84±7.64
Gender	67/138
Application	Anti-Aging
Conclusion	This study provides important evidence from a longitudinal study that fails to support any meaningful association between a transition to family caregiving and telomere shortening over the first 3+ years of the caregiving experience. future work on the tl over time could focus on how caregiving strain, chronicity, or the type of caregiving (e.g., to a parent, spouse, or child; dementia/cognitive impairment or physical impairment caregiver) might be associated with tl. ultimately, more research to address the complex relationship between caregiving and measures of cellular aging is needed to improve the well-being of caregivers and care recipients.
Reference	David L Roth, PLoS One, 2022
Details	PMID:35657918 (Click to Pubmed) ； IF: ； Citation:
Confidence