Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Senescence-Associated Secretory Phenotype (SASP)
Category	Molecular Changes
Affected targets	Reproductive System Aging
Hallmarks	Cellular Senescence
Molecular	Protein
Description	We aimed to investigate the association of circulatory senescence-associated secretory phenotypes (SASPs) produced by senescent cells with chronological and menopausal age in women aged 45 years or more
EXPERIMENT INFORMATION
Region	Asia
Race	yellow
Samples	76
Age	67.6±6.6
Gender	0/76
Application	/
Conclusion	Our findings demonstrate a positive association between select sasp proteins and age-related menopause and confirms that sasp proteins are a relevant physiological?in vivo?marker of aging among postmenopausal women. subsequent studies are needed for further evaluation of whether sasp indicators vary depending on the menopausal state and the potential exposures that induce those consequences.
Reference	Ok Hee Jeon, Rejuvenation Res, 2022
Details	PMID:35583231 (Click to Pubmed) ； IF: ； Citation:
Confidence