The detail information of "Clusterin"

BIOMARKER INFORMATION
Biomarker
Clusterin
Category
Independent Events
Affected targets
Pancreatic Aging
Hallmarks
Cellular Senescence
Molecular
Protein
Description
Clinical studies on the antisense oligonucleotide that targets clusterin (CLU) expression have been conducted and have shown efficacy in other cancers.
EXPERIMENT INFORMATION
Region
Asia
Race
multiple racial
Samples
/
Age
/
Gender
/
Application
Functional
Conclusion
We identified that clu inhibition leads to cellular senescence in pdac. our findings suggest that clu is a novel therapeutic target that contributes to the prognosis of pdac by inducing cellular senescence.
Reference
Suguru Mitsufuji, Ann Surg Oncol, 2022
Details
PMID:35397747 (Click to Pubmed) ； IF: ； Citation:
Confidence

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