The detail information of "Magnetic Resonance Imaging (MRI)"

BIOMARKER INFORMATION
Biomarker
Magnetic Resonance Imaging (MRI)
Category
Imaging Traits
Affected targets
Brain Aging
Hallmarks
Other
Molecular
Other
Description
Statistical effects of cortical metrics derived from standard T1‐ and T2‐weighted magnetic resonance imaging (MRI) images, such as gray–white matter contrast (GWC), boundary sharpness coefficient (BSC), T1‐weighted/T2‐weighted ratio (T1w/T2w), and cortical thickness (CT), are often interpreted as representing or being influenced by intracortical myelin content.
EXPERIMENT INFORMATION
Region
Canada
Race
multiple racial
Samples
174
Age
69.9±5.6/45.8±16.1
Gender
79/95
Application
/
Conclusion
We conclude that the microstructural properties at the source of spatial distributions of mri cortical markers (e.g., gm myelin) can be different from microstructural changes that affect these markers in aging. this warrants care in interpreting the age‐ or disease‐related effects of these mri markers when aiming to show changes in a specific property of the cortical microstructure.
Reference
Olivier Parent, Hum Brain Mapp, 2023
Details
PMID:36896711 (Click to Pubmed) ； IF: ； Citation:
Confidence

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