The detail information of "CD8+ T effector memory RA cells"

BIOMARKER INFORMATION
Biomarker
CD8+ T effector memory RA cells
Category
Cellular Alterations
Affected targets
Hematopietic System Aging
Hallmarks
Altered Intercellular Communication
Molecular
Other
Description
terminally differentiated CD8+ effector memory CD45RA+ TEMRA cells and their subsets have characteristics of cellular senescence, accumulate in older individuals, and are increased in age-related chronic inflammatory diseases.
EXPERIMENT INFORMATION
Region
worldwide
Race
multiple racial
Samples
140
Age
/
Gender
35/105
Application
Anti-Aging
Conclusion
Our findings confirm the association of cd8+ temra and its subsets with cmv infection and provide a novel tool for their high throughput epigenetic quantification as a biomarker of immunosenescence.
Reference
Liina Tserel, Aging Cell, 2022
Details
PMID:35397197 (Click to Pubmed) ； IF: ； Citation:
Confidence

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