Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Oxidative Stress
Category	Cellular Alterations
Affected targets	Hematopietic System Aging
Hallmarks	Mitochondrial Dysfunction
Molecular	Other
Description	In most organisms including humans, telomeres form protective loops by binding to complementary sequences in the overhang itself. The shortening of telomeres has been shown related to the aging of the organism. It has been shown that telomere shortens with age and in several age-associated diseases.Consequently, telomere length (TL) has been suggested as a biomarker of "biological age."
EXPERIMENT INFORMATION
Region	/
Race	/
Samples	105
Age	20-77
Gender	/
Application	Predictive
Conclusion	Taken together, our findings supported the idea of a possible correlation between the tl length and biomarkers of oxidative stress during aging. therefore, prospective and experimental studies are essential to establish a causal relationship between tl and oxidative stress markers and also the possible mechanisms involved. based on our findings, we also propose the utility of antioxidative therapies in the treatment of aging-related diseases. in view of tremendous scope for these novel findings in medical and diagnostics and therapeutics, we believe that these findings will aid oxidative stress studies in human aging.
Reference	Pawan Kumar Maurya, Rejuvenation Res, 2022
Details	PMID:35044242 (Click to Pubmed) ； IF: ； Citation:
Confidence