The detail information of "Oxidative Stress"

BIOMARKER INFORMATION
Biomarker
Oxidative Stress
Category
Cellular Alterations
Affected targets
Hematopietic System Aging
Hallmarks
Mitochondrial Dysfunction
Molecular
Other
Description
Since 1956, it was proposed that the aging is a biological process of every living organism which is related to oxidative stress (OS), and this is defined as a biochemical imbalance between oxidants and antioxidant systems that produces an oxidative damage in biomolecules.
EXPERIMENT INFORMATION
Region
Mexico
Race
yellow
Samples
177
Age
40-69
Gender
0/177
Application
Predictive
Conclusion
It is important to note that in the two-year follow-up cohort of mexican women in the aging process, the older subgroup (60 to 69 years) had significantly higher systolic blood pressure compared to the groups of young women (40 to 49 years) and middle-aged (50 to 59 years) (p <0.001), in addition to a higher prevalence of diabetes mellitus in the older subgroup. also, this group (60 to 69 years) was the one that reported a significantly higher percentage regard to continuing with physical activity (p <0.001). likewise, a significantly higher oxidative stress index was found in the subgroup of older women compared to the younger and middle-aged subgroups (p <0.05). on the other hand, in the global analysis of the population, a positive correlation was observed between age, consumption of coffee cups, number of cigarettes, and score on the insomnia scale with the oxidative stress index, in contrast to a negative association with the moderate consumption of alcoholic beverages and the score on the scale to assess dysthymia. finally, the most relevant finding of our study was that regardless of age and other prooxidant factors, sedentary lifestyle constitutes a statistically significant risk factor for oxidative stress mexican women in the aging process.
Reference
Víctor Manuel Mendoza-Nú?ez, Oxid Med Cell Longev., 2021
Details
PMID:34733404 (Click to Pubmed) ; IF: ; Citation:
Confidence