The detail information of "Atrial Fibrillation"

BIOMARKER INFORMATION
Biomarker
Atrial Fibrillation
Category
Molecular Changes
Affected targets
Cardiac Aging
Hallmarks
Epigenetic Alterations
Molecular
Other
Description
The most prominent risk factor for atrial fibrillation (AF) is chronological age; however, underlying mechanisms are unexplained. Algorithms using epigenetic modifications to the human genome effectively predict chronological age.
EXPERIMENT INFORMATION
Region
Canada,USA
Race
/
Samples
5600
Age
/
Gender
2234/3366
Application
Functional
Conclusion
Our study identified adjusted associations between eaa measures and incident af, suggesting that biological aging plays an important role independent of chronological age, though a potential underlying causal relationship remains unclear. these aging processes may be modifiable and not constrained by the immutable factor of time.
Reference
Gregory M Marcus, Circulation, 2021
Details
PMID:34587750 (Click to Pubmed) ； IF: ； Citation:
Confidence

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