The detail information of "Mitochondrial Energy Metabolism Markers"

BIOMARKER INFORMATION
Biomarker
Mitochondrial Energy Metabolism Markers
Category
Cellular Alterations
Affected targets
Skin Aging
Hallmarks
Mitochondrial Dysfunction
Molecular
DNA
Description
The decline of mitochondrial function throughout the lifespan is directly linked to the development of ageing phenotypes of the skin.
EXPERIMENT INFORMATION
Region
Austria
Race
multiple racial
Samples
43
Age
27.6±1.7)/76.2±1.73
Gender
22/21
Application
Functional
Conclusion
Overall, we demonstrate that ageing is associated with reduced protein levels of complex v of the mitochondrial respiratory chain and tfam. these alterations may impair essential mitochondrial functions, exacerbating the cutaneous ageing process.
Reference
Barbara Kofler, Experimental Dermatology, 2023
Details
PMID:36851889 (Click to Pubmed) ； IF: ； Citation:
Confidence

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