Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Telomeric repeat-containing RNA (TERRA)
Category	Molecular Changes
Affected targets	Skeletal Muscle Aging
Hallmarks	Loss of Proteostasis
Molecular	Other
Description	it turned out that the C-rich strands of human telomeres are transcribed from very distal subtelomeric promoters by the RNA polymerase II, generating telomeric repeat-containing RNA (TERRA) molecules composed of subtelomeric sequences at their 5′ end followed by (UUAGGG)n repeats
EXPERIMENT INFORMATION
Region	Belgium
Race	multiple racial
Samples	34
Age	/
Gender	36586
Application	Functional
Conclusion	The age-dependent increase in terra expression might represent a novel biological marker of aging.
Reference	Louise Deldicque, Experimental Gerontology, 2021
Details	PMID:34371098 (Click to Pubmed) ； IF: ； Citation:
Confidence