Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Emotional Unstable Personality Disorder (EUPD)
Category	Independent Events
Affected targets	Other
Hallmarks	Epigenetic Alterations
Molecular	Other
Description	Emotionally unstable personality disorder (EUPD), also referred to as Borderline Personality Disorder, is a mental disorder marked by a persistent pattern of unstable and intensive interpersonal relationships, efforts to avoid real or perceived abandonment, affective instability, identity disturbance and self-destructive impulsive behavior
EXPERIMENT INFORMATION
Region	Europe
Race	white
Samples	97(EUPD)/32(health)
Age	29.4/37.2
Gender	0/129
Application	Predictive
Conclusion	The results showed that the somatic health effects associated with eupd are severe, as demonstrated by the 32.2% increase in ea measured by the state-of-the-art algorithm grimage, compared to chronological age in a sample of female eupd patients in early adulthood.these results underscore the importance of addressing medical health conditions along with low-cost preventative interventions aimed at improving somatic health outcomes in eupd, such as efforts to support cessation of tobacco use. the independency of grimage to other ea algorithms in this group of severely impaired eupd patients, suggest it may have unique characteristics to evaluate risk of adverse health outcomes in context of psychiatric disorders.
Reference	Jokinen J, Transl Psychiatry, 2023
Details	PMID:36813766 (Click to Pubmed) ； IF: ； Citation:
Confidence