Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Bone Mineral Density (BMD)
Category	Histological Features
Affected targets	Skeletal Aging
Hallmarks	Cellular Senescence
Molecular	Other
Description	hip BMD decreased with aging in men and women
EXPERIMENT INFORMATION
Region	Asia
Race	yellow
Samples	411
Age	50-89
Gender	203/208
Application	Functional
Conclusion	This research was designed to create a cohort that more accurately reflects common residents. bmd decreased with aging in the femoral neck and total hip. on the other hand, there was no characteristic change with aging in the lumber spine. furthermore, all bone markers except for pentosidine and dpd showed no significant independent characteristics associated with age or gender in a multivariate analysis model. however, a significant association between low bmd and tracp-5b in females was observed; therefore, high bone resorption may be a factor for low bmd in female residents.
Reference	Hiroyuki Kato, Sci Rep, 2021
Details	PMID:33837266 (Click to Pubmed) ； IF: ； Citation:
Confidence