The detail information of "Senescence-Associated Secretory Phenotype (SASP)"

BIOMARKER INFORMATION
Biomarker
Senescence-Associated Secretory Phenotype (SASP)
Category
Cellular Alterations
Affected targets
Skeletal Aging
Hallmarks
Cellular Senescence
Molecular
Other
Description
Furthermore, RT-PCR was performed to evaluate the relative expression of osteogenic and adipogenic marker genes as well as the expression of markers for a senescence-associated secretory phenotype (SASP).
EXPERIMENT INFORMATION
Region
Germany
Race
multiple racial
Samples
32
Age
/
Gender
/
Application
Functional
Conclusion
Future research should focus on the identification of specific cell markers on mscprim, which may influence complication rates such as aseptic loosening of total joint arthroplasty to further individualize and optimize total joint arthroplasty.
Reference
Maximilian Rudert, Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022
Details
PMID:33749912 (Click to Pubmed) ; IF: ; Citation:
Confidence