The detail information of "Y-CpGs"

BIOMARKER INFORMATION
Biomarker
Y-CpGs
Category
Molecular Changes
Affected targets
Reproductive System Aging
Hallmarks
Epigenetic Alterations
Molecular
Other
Description
Although DNA methylation (DNAm) variation of autosomal CpGs provides robust age predictive biomarkers, no male-specific age predictor exists based on Y-CpGs yet. Since sex chromosomes play an important role in aging, a Y-chromosome-based age predictor would allow studying male-specific aging effects and would also be useful in forensics.
EXPERIMENT INFORMATION
Region
Netherlands
Race
multiple racial
Samples
1057
Age
15-87
Gender
/
Application
Predictive
Conclusion
Overall, we introduce the first-of-its-kind male-specific epigenetic age predictor for future applications in aging research and forensics.
Reference
Manfred Kayser, Aging, 2021
Details
PMID:33744870 (Click to Pubmed) ； IF: ； Citation:
Confidence

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