The detail information of "DNA Methylation Age"

BIOMARKER INFORMATION
Biomarker
DNA Methylation Age
Category
Molecular Changes
Affected targets
Adipose Tissue Aging
Hallmarks
Epigenetic Alterations
Molecular
Other
Description
DNA methylation (DNAm) age (mAge), a methylation biomarker for the aging process, might serve as a more accurate predictor of morbidity and aging status than chronological age.
EXPERIMENT INFORMATION
Region
Israel, Germany, Denmark, USA and Austria
Race
multiple racial
Samples
120
Age
/
Gender
110/10
Application
Predictive
Conclusion
Lifestyle weight-loss intervention may attenuate maging. deviation of mage from chronological age might be related to body fat distribution and glycemic control and could indicate biological age, health status and the risk for premature cardiometabolic diseases.
Reference
Iris Shai, Clinical epigenetics, 2021
Details
PMID:33663610 (Click to Pubmed) ; IF: ; Citation:
Confidence