The detail information of "Short Telomere"

BIOMARKER INFORMATION
Biomarker
Short Telomere
Category
Molecular Changes
Affected targets
Lung Aging
Hallmarks
Telomere Attrition
Molecular
Other
Description
Chronic obstructive pulmonary disease (COPD) is a disorder of accelerated lung aging. Multiple pieces of evidence support that the aging biomarker short telomeres, which can be caused by mutations in telomerase reverse transcriptase (TERT), contribute to COPD pathogenesis.
EXPERIMENT INFORMATION
Region
/
Race
white
Samples
/
Age
/
Gender
/
Application
Functional
Conclusion
Collectively, our data suggest that functional tert snps with mild catalytic defects are nonetheless implicated in the clinical presentation of copd.
Reference
Judy M Y Wong, Scientific reports, 2021
Details
PMID:33619289 (Click to Pubmed) ； IF: ； Citation:
Confidence

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