The detail information of "Cellular Senescence-Associated Genes"

BIOMARKER INFORMATION
Biomarker
Cellular Senescence-Associated Genes
Category
Molecular Changes
Affected targets
Liver Aging
Hallmarks
Genomic Instability
Molecular
DNA
Description
The cellular senescence-related scoring system was validated as an independent prognostic factor and immunotherapy predictor for HCC, and patients with low CSS were characterized by prolonged survival time.
EXPERIMENT INFORMATION
Region
China
Race
multiple racial
Samples
365
Age
/
Gender
245/120
Application
Predictive
Conclusion
Our study confirmed the relationship between cellular senescence and immune cell infiltration, energy metabolism, chemokines, expression of immune checkpoint-related genes, and response to immunotherapy.
Reference
Shichun Lu, Sci Rep, 2023
Details
PMID:36670201 (Click to Pubmed) ; IF: ; Citation:
Confidence