The detail information of "Deletion of complement factor H-related genes 1 and 3 (delCFHR3-1)"

BIOMARKER INFORMATION
Biomarker
Deletion of complement factor H-related genes 1 and 3 (delCFHR3-1)
Category
Molecular Changes
Affected targets
Kidney Aging
Hallmarks
Cellular Senescence
Molecular
DNA
Description
DelCFHR3-1 mediates cellular senescence through complement
EXPERIMENT INFORMATION
Region
USA
Race
multiple racial
Samples
67
Age
71
Gender
/
Application
Functional
Conclusion
These data support both the role of fhr1 in mediating complement activation and tubular senescence, and suggest the possibility of genotyping delcfhr3-1 to predict graft survival in igan-transplanted patients.
Reference
Francesco Pesce, Am J Transplant, 2021
Details
PMID:33091234 (Click to Pubmed) ； IF: ； Citation:
Confidence

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