The detail information of "Intrarenal Telomere Length"

BIOMARKER INFORMATION
Biomarker
Intrarenal Telomere Length
Category
Molecular Changes
Affected targets
Kidney Aging
Hallmarks
Telomere Attrition
Molecular
DNA
Description
Recently, we demonstrated that arteriosclerosis in the smaller intrarenal arteries is associated with shorter telomere length, independently of history of cardiovascular events and calendar age.
EXPERIMENT INFORMATION
Region
worldwide
Race
multiple racial
Samples
213
Age
48.0±15/48.7±15
Gender
128/85
Application
Functional
Conclusion
In conclusion, our study suggests that there is an association between overexpression of intrarenal cholesterol biosynthesis, shorter intrarenal telomere length and increased renal arteriosclerosis in humans, although no causality can be inferred from our data.
Reference
Maarten Naesens, Aging (Albany NY), 2020
Details
PMID:32353828 (Click to Pubmed) ； IF: ； Citation:
Confidence

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