The detail information of "Cyclin F"

BIOMARKER INFORMATION
Biomarker
Cyclin F
Category
Molecular Changes
Affected targets
Kidney Aging
Hallmarks
Genomic Instability
Molecular
DNA
Description
Further studies showed that the reduction of CCNF promoted cell senescence by decreasing cyclin-dependent kinase 1 (CDK1), increasing the proinflammatory factors interleukin (IL)-6 and IL-8, and then enhancing the expression of p21 and p53.
EXPERIMENT INFORMATION
Region
China
Race
multiple racial
Samples
/
Age
/
Gender
/
Application
Functional
Conclusion
We propose that the high expression of ccnf in kirc may play a key role in tumorigenesis by regulating cell senescence.
Reference
Ya-Qi Chen, Curr Med Sci, 2023
Details
PMID:36602672 (Click to Pubmed) ； IF: ； Citation:
Confidence

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