Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Immunoglobulin G (IgG)
Category	Molecular Changes
Affected targets	Cardiac Aging
Hallmarks	Loss of Proteostasis
Molecular	Protein
Description	binding of autologous immunoglobulin G(IgG) to RBCs occurs at exposure times and stress levels found in cardiovascular devices and conclude that it may be a contributing factor to premature removal of red blood cells in patients with these devices.
EXPERIMENT INFORMATION
Region	USA
Race	multiple racial
Samples	10
Age	18–64
Gender	/
Application	Functional
Conclusion	Measurement of igg holds promise as a marker foreshadowing complications in cardiovascular patients and as a means to improve the design of medical devices in which rbcs are susceptible to sublethal trauma.
Reference	Edgar A O'Rear, Sci Rep, 2019
Details	PMID:31857631 (Click to Pubmed) ； IF: ； Citation:
Confidence