Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	Periostin
Category	Molecular Changes
Affected targets	Skeletal Aging
Hallmarks	Stem Cell Exhaustion
Molecular	Protein
Description	periostin (POSTN), also known as osteoblast-specific factor-2 , physiologically modulates ECM organization playing a unique role in the connection between the cells and the microenvironment that surrounds them and translates signals between ECM and cell.
EXPERIMENT INFORMATION
Region	France,Monaco
Race	multiple racial
Samples	1096
Age	74.96/76.35
Gender	396/700
Application	Predictive
Conclusion	Our study showed for the first time that increased plasma periostin levels were associated with declines in both physical and cognitive capacities in older adults over a 4-year follow-up.
Reference	Philipe de Souto-Barreto, Journals of Gerontology Series A-biological Sciences And Medical Sciences, 2023
Details	PMID:36373873 (Click to Pubmed) ； IF: ； Citation:
Confidence