The detail information of "DNA Methylation (DNAm)"

BIOMARKER INFORMATION
Biomarker
DNA Methylation (DNAm)
Category
Molecular Changes
Affected targets
Cardiac Aging
Hallmarks
Epigenetic Alterations
Molecular
DNA
Description
Methylation status at these CpG sites has been reported to relate to chronic diseases, including metabolic syndrome, heart disease, stroke, cancer, and mortality, even after adjusting for age and other traditional risk factors.
EXPERIMENT INFORMATION
Region
USA
Race
multiple racial
Samples
2435
Age
54.9±14.3
Gender
697/817
Application
Functional
Conclusion
In the current study, we provide evidence to suggest that habitual physical activity and sedentary time were associated with dna methylation status on markers associated with mortality and older age. bmi only partially explains these associations. further research could explore whether these and other markers of methylation status can be modified by changes in lifestyle habits and whether those modifications to methylation status confer influence on disease risk.
Reference
Nicole Spartano, Med Sci Sports Exerc, 2023
Details
PMID:36107108 (Click to Pubmed) ； IF: ； Citation:
Confidence

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