The detail information of "Neuroplasticity"

BIOMARKER INFORMATION
Biomarker
Neuroplasticity
Category
Independent Events
Affected targets
Brain Aging
Hallmarks
Chronic Inflammation
Molecular
Other
Description
Neuroplasticity can be broadly defined as a change in neural structure and function in response to experience or environmental stimuli. Neuroplasticity is a critically important mechanism for brain health, as it underlies the capacity of the nervous system to change and adapt to the ever-changing demands of the human experience. Neuroplasticity is the underlying mechanism for cognitive and motor learning and is critically involved in the ability to maintain cognitive health and independence during aging.
EXPERIMENT INFORMATION
Region
USA
Race
multiple racial
Samples
30
Age
60.6±3.8
Gender
45615
Application
Predictive
Conclusion
Our findings strengthen the theoretical framework linking the brain-heart pathway, as we demonstrate that neuroplasticity, as assessed by tms/itbs, was associated with well-established clinical outcomes of cardiovascular health. this finding builds on existing data demonstrating that tms may provide insight into neuroplasticity and the role of exercise, and cardiovascular health appears to have on its mechanisms. the data can also contribute to the field by providing an easy, safe, and well-established cardiovascular health measure, the hrr1, as a predictor of mechanisms of neuroplasticity in aging adults. we also were able to explore preliminary results on the role of circulating markers of endothelium function on neuroplasticity mechanisms and cardiovascular health. these implications can serve as theoretical framework for future longitudinal and interventional studies aiming to influence attitudes towards to change behavior aiming to improve cardiovascular health, and subsequently improve brain health in this population. clinicians would benefit from this study by including hrr1 as a potential screening and prognostic measure of cardiovascular health and as a surrogate marker of brain health.
Reference
Danylo F Cabral, Auton Neurosci., 2022
Details
PMID:36087362 (Click to Pubmed) ； IF: ； Citation:
Confidence

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