Aging-BC_Biomarker

BIOMARKER INFORMATION
Biomarker	8-iso-prostaglandin F2α
Category	Molecular Changes
Affected targets	Eye Aging
Hallmarks	Other
Molecular	Other
Description	One of the major F2-isoprostanes, 8-iso-prostaglandin F2a (PGF2a), is formed during free radical-catalyzed peroxidation of arachidonic acid and is one of the most reliable biomarkers of oxidative stress in vivo
EXPERIMENT INFORMATION
Region	Sweden
Race	multiple racial
Samples	516(258/258)
Age	71.2±6.9/71.2±6.8
Gender	516/0
Application	Functional
Conclusion	Systemic oxidative stress as measured by urinary f2-isoprostane, 8-iso-pgf2a, may be associated with increased risk of age-related cataract.
Reference	Alicja Wolk, Antioxid Redox Signal., 2014
Details	PMID:24527727 (Click to Pubmed) ； IF: ； Citation:
Confidence